Direct Meds vs MEDVi
Direct Meds and MEDVi both sell semaglutide; this is how their prices, coverage and records differ.
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If you are choosing between Direct Meds and MEDVi, price alone will not settle it. Both prescribe semaglutide, so moving from one to the other would not change your drug. MEDVi leads our six-part score, 7.1 to 6.4. Both have drawn an FDA warning letter.
Direct Meds vs MEDVi price
Direct Meds and MEDVi start at the same figure, $249 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $249 a month.
Medications and formats
Both sell semaglutide; only Direct Meds lists tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Direct Meds does not publish where it ships, and MEDVi lists 48 states.
Pricing
Direct Meds
'As low as $249' per month, on a 90-day supply billed monthly; some doses run as low as $237/mo.
'As low as $297' per month ($9.58 a day), an 84-day three-pack billed monthly.
'As low as $299' per month ($9.65 a day) on a 90-day supply billed monthly. Down from $399 earlier.
'As low as $399' per month ($12.87 a day).
MEDVi
Refills are locked in at $299. The first month is $179 in the 'SUMMER Sale,' and some MEDVi landing pages offer the first month at $149.
Flat 'Starting at $249' — no intro discount shown.
$99 Membership + Medication Cost — medication cost not published (varies/insurance may reimburse). 'Availability is subject to change.'
$99 Membership + Medication Cost — medication cost not published. COMPOUNDED tirzepatide ($349 in our current entry) is no longer published anywhere on glp1.medvi.org, home.medvi.org, or the intake flow (0 mentions) — treat as discontinued/not published, do not carry the $349 row forward.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
MEDVi's price also covers coaching, which Direct Meds does not claim.
Direct Meds is silent on lab work and coaching.
MEDVi is silent on lab work.
Direct Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
MEDVi
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Where each one scores higher
Overall, MEDVi scores 7.1 and Direct Meds 6.4 out of 10.
Direct Meds is stronger on value (3.7 vs 2.8).
MEDVi is stronger on trust & safety (6.0 vs 3.5), accessibility (9.7 vs 5.0) and support (8.5 vs 7.0).
Effectiveness and user experience are within half a point.
Direct Meds
6.4/10
MEDVi
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Direct Meds a warning letter dated September 9, 2025 (letter 716822), and it is still open.
The FDA sent MEDVi a warning letter dated February 20, 2026 (letter 721455), and it is still open.
Features & Coverage
| Feature | Direct Meds | MEDVi |
|---|---|---|
| Starting Price | $249/mo | $249/mo |
| Features | 5 features | ✓7 features |
| States Available | Not disclosed | 48 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | 1 letter |
About Direct Meds
The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.
Read our full Direct Meds review →About MEDVi
Two clinical groups do the treating at MEDVi: CareGLP Affiliated P.C.s, plus clinicians from OpenLoop Health. Its weight-loss menu holds compounded GLP-1s, injections and tablets alike, the molecule being semaglutide, next to Zepbound and Wegovy under their brand names. Licensed US pharmacies fill all of it.
Read our full MEDVi review →Pros & Cons
Direct Meds
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Direct Meds a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
MEDVi
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits, shipping and coaching
- Serves 48 states
- Names 3 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- The FDA has issued MEDVi a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Direct Meds is where we would start, above all for compounded semaglutide at $249/month. MEDVi fits better if knowing which pharmacy fills the vial: it names Triad Rx is your priority.
Choose Direct Meds if…
You want compounded semaglutide at $249/month and an opening price near $249 a month.
Choose MEDVi if…
You want knowing which pharmacy fills the vial: it names Triad Rx and an opening price near $249 a month.
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He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Direct Meds vs MEDVi: FAQ
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- MEDVi vs Cabana
- MEDVi vs Next Vial
Or see the full category ranking.