GLP Watchdog

Direct Meds vs MangoRx

Direct Meds has an open FDA warning letter dated September 9, 2025. MangoRx has none. On compounded oral semaglutide, Direct Meds costs $600 less a year at standing rates: $249 a month against $299 a month at MangoRx.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Direct Meds / MangoRx

Direct Meds logo

Direct Meds

7.1/10

MangoRx logo

MangoRx

6.5/10

FDA warning letters
None on record
Pharmacy
None named in our record
None named in our record
Lowest standing price
$249/moCompounded oral semaglutide
$299/moCompounded oral semaglutide
States
48 states and DC
46 states and DC
Checked
Prices captured Record checked October 2026
Prices captured Record checked October 2026
Visit Direct Meds
Visit MangoRx

Both Direct Meds and MangoRx are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (Direct Meds 7.1, MangoRx 6.5). How we are paid

What the record shows

  1. 01

    Direct Meds has an open FDA warning letter dated September 9, 2025. MangoRx has none.

  2. 02

    Neither names the pharmacy that compounds its medication.

  3. 03

    On compounded oral semaglutide, Direct Meds costs $600 less a year at standing rates: $249 a month against $299 a month at MangoRx.

  4. 04

    Only Direct Meds lists a price for compounded semaglutide injection, compounded tirzepatide injection and compounded oral tirzepatide.

  5. 05

    Direct Meds covers three states MangoRx does not and MangoRx covers one state Direct Meds does not.

  6. 06

    Direct Meds holds you to a 90-day supply shipped at once, remaining months billed every 30 days; MangoRx states you can cancel at any time.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Direct Meds

MangoRx

Compounded oral semaglutide

$249/moLower

$2,988 a year

$299/mo

$3,588 a year

Compounded semaglutide injection

$297/mo

$3,564 a year

Not sold or not priced
Compounded tirzepatide injection

$399/mo

$4,788 a year

Not sold or not priced
Compounded oral tirzepatide

$299/mo

$3,588 a year

Not sold or not priced
Price includes
Medication, clinician visits, shipping
Medication, clinician visits
Cancel any time
No
Yes, stated
Minimum term
90-day supply shipped at once, remaining months billed every 30 days
None: "Billed monthly. Cancel anytime."
Refunds
No refunds for medication already received; $35 disposal fee on returns
Full refund if declined; "all sales are final once fulfilled". Refund policy bills $80 (video) or $70 (phone) when a GLP-1 consult ends without a prescription.

Read off each seller’s own pages. Direct Meds: October 17, 2026. MangoRx: October 17, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Direct Meds

7.1/10
  • $600 a year less on compounded oral semaglutide
  • Sells compounded semaglutide injection and compounded tirzepatide injection, which MangoRx does not price
  • Open FDA warning letter, September 9, 2025
  • Names no compounding pharmacy
  • Minimum commitment before you can cancel
Visit Direct Meds

The case for MangoRx

6.5/10
  • No FDA warning letter on record
  • States you can cancel at any time
  • Names no compounding pharmacy
Visit MangoRx

Scores

Direct Meds 7.1 · MangoRx 6.5 out of 10. Six weighted parts.

Value25%

4.2A
vs
B
2.1

Effectiveness25%

10.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

4.5A
vs
B
7.5

Accessibility10%

9.7A
vs
B
9.4

Support10%

7.0A
vs
B
5.5

The score is the same formula for every seller. Payment does not enter it. Method

Direct Meds vs MangoRx: questions

Direct Meds has an open FDA warning letter dated September 9, 2025. MangoRx has none. Letters are matched to a seller by company, domain and address, never by a similar name.
Neither names the pharmacy that compounds its medication.
Direct Meds, by $600 a year at standing rates. Direct Meds: $249 a month, about $2,988 a year. MangoRx: $299 a month, about $3,588 a year.
Direct Meds has a minimum term (90-day supply shipped at once, remaining months billed every 30 days). MangoRx states you can cancel at any time; refunds: full refund if declined; "all sales are final once fulfilled". refund policy bills $80 (video) or $70 (phone) when a glp-1 consult ends without a prescription.
Both Direct Meds and MangoRx are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (Direct Meds 7.1, MangoRx 6.5).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register