Direct Meds vs Hims
Hims costs $50 less a month, and both sell semaglutide and tirzepatide.
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Hims
Best for: knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC
Visit Hims →If you are choosing between Direct Meds and Hims, the first difference is cost: Hims is $50 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Hims leads our six-part score, 6.8 to 6.4. Both have drawn an FDA warning letter.
Direct Meds vs Hims price
Hims is the cheaper way in: $199 a month against $249 a month at Direct Meds. That is $50 less each month (20% lower), or about $600 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Hims ($199 a month vs $249 a month); tirzepatide costs the same at both, $299 a month.
Medications and formats
Both sell semaglutide and tirzepatide.
On format, Direct Meds prices compounded injections, while Hims prices compounded injections and brand-name pens.
If you want the FDA-approved brand rather than a compounded version, Hims is the only one of the two with a brand-name price.
Where each one treats patients
Direct Meds does not publish where it ships, and Hims lists 50 states.
Pricing
Direct Meds
'As low as $249' per month, on a 90-day supply billed monthly; some doses run as low as $237/mo.
'As low as $297' per month ($9.58 a day), an 84-day three-pack billed monthly.
'As low as $299' per month ($9.65 a day) on a 90-day supply billed monthly. Down from $399 earlier.
'As low as $399' per month ($12.87 a day).
Hims
Brand Zepbound from $299/mo medication-only; requires Hims Weight Loss Membership ($149/mo)
What each price covers
Both prices cover the medication itself.
Direct Meds' price also covers the clinician visit and shipping, which Hims does not claim.
Direct Meds is silent on lab work and coaching.
Hims is silent on shipping and lab work.
Direct Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Hims
Covered by the monthly price
Medication
In the price
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Not stated
Coaching
Charged on top
Where each one scores higher
Overall, Hims scores 6.8 and Direct Meds 6.4 out of 10.
Direct Meds is stronger on value (3.7 vs 3.0) and support (7.0 vs 3.0).
Hims is stronger on trust & safety (7.0 vs 3.5) and accessibility (10.0 vs 5.0).
Effectiveness and user experience are within half a point.
Direct Meds
6.4/10
Hims
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Direct Meds a warning letter dated September 9, 2025 (letter 716822), and it is still open.
The FDA sent Hims a warning letter dated September 9, 2025 (letter 716567), and it is still open.
Features & Coverage
| Feature | Direct Meds | Hims |
|---|---|---|
| Starting Price | $249/mo | ✓$199/mo |
| Features | ✓5 features | 2 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | 1 letter |
About Direct Meds
The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.
Read our full Direct Meds review →About Hims
Hims is a major men's telehealth brand. Its weight loss offering is compounded semaglutide on a 6-month plan.
Read our full Hims review →Pros & Cons
Direct Meds
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Direct Meds a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Hims
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication
- Serves all 50 states
- Names 4 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Not included in the monthly price: clinician visits, coaching
- The FDA has issued Hims a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Direct Meds is where we would start, above all for compounded semaglutide at $249/month. Hims undercuts it by $50 a month, so if the monthly bill is what decides it, Hims is the pick. Hims fits better if knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC is your priority.
Choose Direct Meds if…
You want compounded semaglutide at $249/month and an opening price near $249 a month.
Choose Hims if…
You want knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC and an opening price near $199 a month.
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Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →Direct Meds vs Hims: FAQ
Close alternatives to Direct Meds and Hims
- Direct Meds vs Henry Meds
- Direct Meds vs Fridays
- Direct Meds vs Luvo Health
- Direct Meds vs RxSpan MD
- Hims vs Hers
- Hims vs Noom
Or see the full category ranking.
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