altRX vs PlushCare
altRX and PlushCare both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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PlushCare
Best for: coverage in all 50 states, which most sellers will not confirm
Visit PlushCare →If you are choosing between altRX and PlushCare, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. altRX leads our six-part score, 6.7 to 6.4. One of the two has an FDA warning letter on record, covered below.
altRX vs PlushCare price
altRX and PlushCare start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at altRX ($249 a month vs $399 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, altRX prices compounded injections and brand-name pens, while PlushCare prices compounded injections.
If you want the FDA-approved brand rather than a compounded version, altRX is the only one of the two with a brand-name price.
Where each one treats patients
altRX does not publish where it ships, and PlushCare lists 50 states.
Pricing
altRX
PlushCare
Range up to $299/mo
Range up to $599/mo
What each price covers
altRX's price also covers the clinician visit, the medication itself and shipping, which PlushCare does not claim.
altRX is silent on lab work and coaching.
PlushCare is silent on shipping and coaching.
That matters most for the drug: unless PlushCare confirms otherwise, budget for medication on top of its listed price.
altRX
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
PlushCare
Covered by the monthly price
Medication
Charged on top
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Charged on top
Coaching
Not stated
Where each one scores higher
Overall, altRX scores 6.7 and PlushCare 6.4 out of 10.
altRX is stronger on value (5.0 vs 3.0), user experience (8.0 vs 7.0) and support (7.0 vs 0.0).
PlushCare is stronger on trust & safety (7.5 vs 3.5) and accessibility (10.0 vs 5.0).
Effectiveness is within half a point.
altRX
6.7/10
PlushCare
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent altRX a warning letter dated June 8, 2026 (letter 728236), and it is still open.
PlushCare has no FDA warning letter on record with us.
Features & Coverage
| Feature | altRX | PlushCare |
|---|---|---|
| Starting Price | $149/mo | $149/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About altRX
Compounded plans open at $149 for semaglutide and $249 for tirzepatide. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer.
Read our full altRX review →About PlushCare
PlushCare is an established virtual primary-care telehealth platform and a subsidiary of Transcarent, Inc., a Delaware corporation that also owns Accolade, 2nd.MD, and 98point6 by Transcarent. Virtual visits with US board-certified physicians cost $30 per appointment insured and $129 self-pay. GLP-1 prescribing is a clinician-discretionary option within the broader primary-care relationship.
Read our full PlushCare review →Pros & Cons
altRX
What we like
- Tirzepatide costs $1249 a month, close to the $1249 median for brand-name tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $1149 a month, 16% above the $990 median for brand-name semaglutide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued altRX a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
PlushCare
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- Serves all 50 states
- We found no FDA warning letters issued to PlushCare
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- Not included in the monthly price: medication, clinician visits, lab work
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
altRX wins this one, 6.7 to 6.4, above all for semaglutide from $1149/month. PlushCare fits better if coverage in all 50 states, which most sellers will not confirm is your priority.
Choose altRX if…
You want semaglutide from $1149/month and an opening price near $149 a month.
Choose PlushCare if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $149 a month.
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RNK Health
An oral route if you will not self-inject
From $197/mo
Get started →He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →altRX vs PlushCare: FAQ
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.