Silhouette MD Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.3/10
Best for: an oral route if you will not self-inject
Silhouette MD falls below our bar on disclosure. Read the breakdown below before you give it money.
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Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
Charged on top
Prices checked June 2026
OpenLoop Health, the licensed clinical partner here, both writes the prescription and fulfills it. Every plan carries provider oversight plus full-service support, with no higher tier to buy. Two compounded GLP-1 molecules are stocked, semaglutide and tirzepatide, each available as a shot or taken by mouth. The positioning is concierge-style.
Is Silhouette MD legit?
Yes. Silhouette MD is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 6.3/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Silhouette MD promo or coupon code?
We know of no promo or coupon code for Silhouette MD. Its listed price is $149 a month. Coupon sites advertising "Silhouette MD discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how Silhouette MD compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to Silhouette MD
Editorial score · methodology
Editorial score · methodology
Embody
Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy
Editorial score · methodology
Silhouette MD at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $149/mo
- What's included
- Medication · Consult
- FDA status
- No FDA warning letters found
How Silhouette MD scores
Six columns, each one computed from something Silhouette MD has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
6.6/10$149/month is 19% below the $185 median for compounded semaglutide across the sellers we compare.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
3.0/10No price appears until the medical intake is finished.
Trust & Safety15%
4.0/10No pharmacy is named for its prescriptions. Its price appears only after the medical intake.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
5.5/10The price covers the medication and clinician visits.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Silhouette MD
Last checked June 2026- Checked the listed price across 4 dose or plan tiers
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for Silhouette MD
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with Silhouette MD involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1Silhouette MD shows a price only after you finish its medical questionnaire, so you cannot compare costs until you have shared health information.
- 2Ask Silhouette MD which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication and clinician visits.
- Lowest ongoing monthly price: semaglutide $149, tirzepatide $299. That leaves out membership fees, first-month rates and insurance copays.
- Confirm that Silhouette MD serves your state before you start.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
GLP-1 medications Silhouette MD offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
Lowest advertised tier ('as low as').
Lowest advertised tier ('as low as').
Oral formulation; lowest advertised tier.
Oral formulation; lowest advertised tier.
Check the price yourself before you pay
Every figure here was read off Silhouette MD's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
- The monthly price includes the medication and clinician visits
- We found no FDA warning letters issued to Silhouette MD
Against it
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: coaching
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What Silhouette MD charges
Silhouette MD charges $149/month. That sits at the affordable end of what we see.
- Compounded semaglutide: $149/month
- Compounded tirzepatide: $299/month
- Compounded semaglutide: $263/month
- Compounded tirzepatide: $325/month
For compounded semaglutide, the median across the sellers we compare is $185/month, so Silhouette MD's $149 is genuinely below the middle, not just advertised that way.
Found, at about $149/month, is the closest like-for-like alternative we review.
What Silhouette MD dispenses
Silhouette MD prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two molecules with the largest published weight-loss trial programs behind them. The medication is compounded rather than dispensed as an approved pen. Compounding serves real clinical needs and is entirely lawful; what it is not is reviewed, and the cost difference reflects that.
A needle-free oral option is genuinely uncommon and is the reason some readers will look at Silhouette MD at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.
Safety and disclosure
Before you start an intake, ask Silhouette MD which states it serves, which pharmacy fills its prescriptions and what the monthly price includes. We found no FDA warning letters issued to Silhouette MD. The pharmacy question matters most here because the medication is compounded. If Silhouette MD will not name the pharmacy, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether Silhouette MD bills your plan before you start.
It fits if
- the lowest standing monthly cost is what you are solving for
- injections are the thing keeping you from starting
Our read
Silhouette MD competes on price: $149/month. The catch is disclosure, which is why Silhouette MD scores low on Trust & Safety: settle the pharmacy and pricing questions above before the price decides for you.
The Bottom Line
Silhouette MD falls below our bar on disclosure. Read the breakdown below before you give it money.
Before you pay Silhouette MD
Starting at $149 a month. Check today's price, then start the intake.
Where Silhouette MD is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare Silhouette MD head to head
The sellers closest to Silhouette MD on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Silhouette MD review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of June 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Silhouette MD's current pricing
Plans start at $149 a month. Whether you qualify is a clinician's decision, made after your intake.