GLP Watchdog

Pillar Guide

GLP-1 Medication Guides for Patients

In-depth guides to semaglutide, tirzepatide and the rest of the GLP-1 family: how they work, dosing, comparisons, and what the evidence shows.

No guide in this pillar makes a claim without a source behind it — FDA documents, trial reports, peer-reviewed papers. Both are laid out, in our methodology and the full central citation registry.

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Guides in this pillar

Semaglutide or Tirzepatide: Which Should You Start On?

Semaglutide against tirzepatide: efficacy from the STEP and SURMOUNT trials, side effects, cost, availability, and which one fits you.

Updated April 6, 2026

Ozempic vs Wegovy Price: Why One Costs More

One molecule, semaglutide, sold under two names at different doses and approved by the FDA for different things. We explain the pricing arbitrage and which to choose.

Updated April 6, 2026

Mounjaro vs Zepbound Cost: Which One Insurance Pays For

Mounjaro and Zepbound are both tirzepatide: same drug, different FDA approvals. Here's what's actually different and which one is right for you.

Updated April 6, 2026

Semaglutide Dose Steps: What Each One Feels Like and How to Tolerate It

Week-by-week semaglutide titration chart, what to expect at each dose, side effect timing, and when to ask your prescriber to slow down or hold steady.

Updated April 6, 2026

How GLP-1 Drugs Actually Work in Your Body

How semaglutide and tirzepatide change appetite, gastric emptying and brain signaling, in plain English, and why tirzepatide's dual action matters.

Updated April 6, 2026

Tirzepatide Dose Steps: What Each One Is For and How to Tolerate It

The complete tirzepatide dosing schedule from 2.5 mg to 15 mg, why slow titration matters, how to handle a dose you have missed, and when to adjust for side effects.

Updated April 6, 2026

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