From the FDA label (DailyMed)Verified 2026-06-01

Wegovy Dosing & Titration Schedule

Where semaglutide begins, every step it climbs, and where it stops — maintenance and maximum both — read straight off the FDA prescribing information.

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Wegovy Titration Schedule

Each rung of the Wegovy ladder, taken from Dosage & Administration in its FDA label (DailyMed SetID ee06186f-2aa3-4990-a760-757579d8f77b). The schedule you actually follow is the one your prescriber writes; this is the reference behind it, not advice about your case.

Step	Dose	When
1	0.25 mg once weekly	Weeks 1–4
2	0.5 mg once weekly	Weeks 5–8
3	1 mg once weekly	Weeks 9–12
4	1.7 mg once weekly	Weeks 13–16
5	2.4 mg once weekly	From week 17 on — the maintenance dose

Source: Wegovy FDA prescribing information via DailyMed (SetID ee06186f-2aa3-4990-a760-757579d8f77b), Section 2 Dosage & Administration, read on 2026-06-01. Treat this as a summary: the full label is the document, and your prescriber's instructions are what you follow.

Wegovy Dosing at a Glance

Starting dose

0.25 mg injected subcutaneously once weekly for 4 weeks

Maintenance dose

For weight reduction: 1.7 mg or 2.4 mg (recommended) once weekly. Patients who tolerate 2.4 mg for at least 4 weeks may be increased to a maximum of 7.2 mg once weekly.

Maximum dose

7.2 mg once weekly

How to titrate safely

A dose you cannot tolerate is a reason for your prescriber to hold the ladder for 4 weeks rather than push through. Going faster than the published schedule is not an option.

One rule governs the whole ladder: you only climb if you are tolerating where you already are, and you hold or slow down when side effects flare. Outrunning the label's schedule does not get you results sooner. What it reliably produces is more nausea and more of everything else the gut does in response.

If you miss a dose or can't tolerate a step

Missed a dose? How late is too late is not the same answer for every drug. Read GLP-1 missed-dose rules by drug for what Wegovy specifically allows, before you double up or write the dose off.

Can't tolerate a dose increase? Holding at the current dose, or waiting longer before the next step, is something the label explicitly permits. What each step tends to bring is set out on the Wegovy side effects page, then talk to your prescriber before changing your schedule.

Compare every Wegovy provider

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Frequently Asked Questions

Wegovy (semaglutide) opens at 0.25 mg injected subcutaneously once weekly for 4 weeks — the initiation dose written into its FDA label, DailyMed SetID ee06186f-2aa3-4990-a760-757579d8f77b. It exists to let your body adjust, and as a rule it is not the dose that produces the full effect.

A dose you cannot tolerate is a reason for your prescriber to hold the ladder for 4 weeks rather than push through. Going faster than the published schedule is not an option. What governs you is the schedule written on your own prescription. The ladder above is the label's escalation, not advice about your case.

Its FDA label caps Wegovy at 7.2 mg once weekly, and puts maintenance at For weight reduction: 1.7 mg or 2.4 mg (recommended) once weekly. Patients who tolerate 2.4 mg for at least 4 weeks may be increased to a maximum of 7.2 mg once weekly..

Late-dose windows are drug-specific, so check the missed-dose guide rather than assuming. Where a step up brings side effects you cannot live with, the label permits holding at the current dose or dropping back to the previous one — but raise it with your prescriber rather than deciding on your own. The Wegovy side-effects page sets out what each step tends to bring.