From the FDA label (DailyMed)Verified 2026-06-01

Wegovy Dosing & Titration Schedule

Where semaglutide begins, every step it climbs, and where it stops — maintenance and maximum both — read straight off the FDA prescribing information.

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Wegovy Titration Schedule

Each rung of the Wegovy ladder, taken from Dosage & Administration in its FDA label (DailyMed SetID ee06186f-2aa3-4990-a760-757579d8f77b). The schedule you actually follow is the one your prescriber writes; this is the reference behind it, not advice about your case.

StepDoseWhen
10.25 mg once weeklyWeeks 1–4
20.5 mg once weeklyWeeks 5–8
31 mg once weeklyWeeks 9–12
41.7 mg once weeklyWeeks 13–16
52.4 mg once weeklyFrom week 17 on — the maintenance dose

Source: Wegovy FDA prescribing information via DailyMed (SetID ee06186f-2aa3-4990-a760-757579d8f77b), Section 2 Dosage & Administration, read on 2026-06-01. Treat this as a summary: the full label is the document, and your prescriber's instructions are what you follow.

Wegovy Dosing at a Glance

Starting dose
0.25 mg injected subcutaneously once weekly for 4 weeks
Maintenance dose
For weight reduction: 1.7 mg or 2.4 mg (recommended) once weekly. Patients who tolerate 2.4 mg for at least 4 weeks may be increased to a maximum of 7.2 mg once weekly.
Maximum dose
7.2 mg once weekly

How to titrate safely

A dose you cannot tolerate is a reason for your prescriber to hold the ladder for 4 weeks rather than push through. Going faster than the published schedule is not an option.

One rule governs the whole ladder: you only climb if you are tolerating where you already are, and you hold or slow down when side effects flare. Outrunning the label's schedule does not get you results sooner. What it reliably produces is more nausea and more of everything else the gut does in response.

If you miss a dose or can't tolerate a step

Missed a dose? How late is too late is not the same answer for every drug. Read GLP-1 missed-dose rules by drug for what Wegovy specifically allows, before you double up or write the dose off.

Can't tolerate a dose increase? Holding at the current dose, or waiting longer before the next step, is something the label explicitly permits. What each step tends to bring is set out on the Wegovy side effects page, then talk to your prescriber before changing your schedule.

Compare every Wegovy provider

Your dose and your titration plan are set by a prescriber before anything is written. Current price, verification status, product form and the states each seller ships to are all on one screen.

Frequently Asked Questions