Missed dose guidance · FDA prescribing information

GLP-1 Missed Dose Guide

Select your GLP-1 medication and enter when you were supposed to take it. This tool calculates the time elapsed and gives you drug-specific guidance — sourced verbatim from each FDA prescribing information label — on whether to take the missed dose now or skip and wait for your next scheduled dose.

Select Your Medication

No two of these labels answer the question the same way.

Quick Reference: All Drugs

Every drug's window, set beside the others, as its label states it.

Drug	Frequency	Makeup window	Min spacing
Wegovy semaglutide 2.4 mg	Weekly	5 days (120 hrs)	2 days (48 hrs)
Ozempic semaglutide 0.5 / 1 / 2 mg	Weekly	5 days (120 hrs)	2 days (48 hrs)
Zepbound tirzepatide	Weekly	4 days (96 hrs)	3 days (72 hrs)
Mounjaro tirzepatide	Weekly	4 days (96 hrs)	3 days (72 hrs)
Foundayo orforglipron	Daily	N/A (skip missed dose)	—

Drawn from the prescribing information for Foundayo [5], Mounjaro [4], Zepbound [3], Ozempic [2] and Wegovy [1].

Medical disclaimer

Educational reference only, and no replacement for what your prescriber tells you. The rules quoted above are the labels’ own words, not our paraphrase of them. Several doses missed in a row, side effects underway, or simply not knowing what to do — all three are reasons to call your prescriber or pharmacist before you act.

What each label actually says

Every one of these drugs sets its own rule for a missed dose, in its own label. What separates them is the window: how long after the day it was due a dose can still be taken at all.

Wegovy (semaglutide 2.4 mg) [1]. Inside 5 days of the scheduled day, take it as soon as you can. Past 5 days, let it go and take the next one when it falls due. Two or more missed in a row is a different situation: going back to a lower dose can spare you the GI effects of restarting at full strength, and that is a call for your prescriber.
Ozempic (semaglutide 0.5/1/2 mg) [2]. The same 5 days. Inside it, take the dose; past it, skip and pick the schedule back up.
Zepbound (tirzepatide) [3]. A shorter window, 4 days — 96 hours. Inside it, take the dose as soon as you can; past it, skip to the next scheduled one. Whatever happens, leave at least 3 days (72 hours) between any two doses.
Mounjaro (tirzepatide) [4]. Identical to Zepbound: 4 days, 96 hours, and never less than 3 days between doses.
Foundayo (orforglipron) [5]. A daily tablet rather than a weekly injection, so there is no window to speak of. Miss one and it is simply missed; take the next at its usual time. Never two in a day.

Why the windows differ

It comes down to how long each molecule lasts. Semaglutide has a half-life near 7 days and tirzepatide near 5, which is exactly why Wegovy and Ozempic can allow 5 days to make a dose up while Zepbound and Mounjaro allow 4. The reason for any limit at all is the same in both cases: a late dose landing too near the next one puts two peaks on top of each other, and the side effects follow.

Orforglipron (Foundayo) is a daily oral GLP-1 with a much shorter half-life (~25-35 hours), so the guidance is simply to skip and take the next day’s dose at the regular time.

Important disclaimer

This tool is for educational reference only and does not constitute medical advice. The missed-dose rules are sourced directly from each drug’s FDA prescribing information. If you have missed multiple consecutive doses or are unsure what to do, contact your prescribing clinician. Never double a dose unless specifically instructed by your prescriber.

References

1.Novo Nordisk Inc. WEGOVY (semaglutide) injection, for subcutaneous use — US Prescribing Information. Section 2.3 Missed Doses. FDA Approved Labeling. 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215256s026lbl.pdf
2.Novo Nordisk Inc. OZEMPIC (semaglutide) injection, for subcutaneous use — US Prescribing Information. Section 2.2 Missed Doses. FDA Approved Labeling. 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/209637s020lbl.pdf
3.Eli Lilly and Company. ZEPBOUND (tirzepatide) injection, for subcutaneous use — US Prescribing Information. Section 2.1 Dosage and Administration, Missed Doses. FDA Approved Labeling. 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/217806s002lbl.pdf
4.Eli Lilly and Company. MOUNJARO (tirzepatide) injection, for subcutaneous use — US Prescribing Information. Section 2.1 Dosage and Administration, Missed Doses. FDA Approved Labeling. 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215866s039lbl.pdf
5.Eli Lilly and Company. FOUNDAYO (orforglipron) capsules, for oral use — US Prescribing Information. Section 2.1 Dosage and Administration, Missed Doses. FDA Approved Labeling. 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/foundayo-label.pdf

Related tools and research

GLP-1 dose plotter — visualize how drug levels change when you miss a dose
GLP-1 washout calculator — see how long each drug stays in your system after the last dose
GLP-1 unit converter — mg to syringe units for compounded GLP-1 vials
Mounjaro KwikPen click & dose chart — pen colors, titration, and administration for Mounjaro
Switching between GLP-1 medications — guidance on transitioning between drugs
How to inject semaglutide & tirzepatide — step-by-step injection technique
Side-effect timeline tool — when each side effect peaks and resolves, by drug and week, with verbatim primary-source quotes on every cell.

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