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Lttl vs PlushCare

Lttl and PlushCare both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Lttl logo

Lttl

8.0
★★★★☆4/5

Best for: starting below a standard dose, with microdose tiers

Visit Lttl →
VS
PlushCare logo

PlushCare

6.4
★★★☆☆3.2/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit PlushCare →

If you are choosing between Lttl and PlushCare, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Lttl leads our six-part score, 8.0 to 6.4.

Lttl vs PlushCare price

Lttl and PlushCare start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at Lttl ($149 a month vs $399 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Lttl does not publish where it ships, and PlushCare lists 50 states.

Pricing

Lttl

Injectable, monthly auto-refill (flat across all dosages)Compounded
$199$149/mo
Save 25% right now
semaglutide

Month-to-month 'Monthly Auto-Refill' rate, was $249. Commitment ladder published on /plans: $169/mo billed $507 quarterly, $149/mo billed $894 every 6mo, $129/mo billed $1,548 annually. Promo is a one-time 'First Month Special' at $149 ('$149 - first month only'). The homepage 'Plans start at $129/mo' headline is the 12-month prepay rate.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$279$199/mo
Save 29% right now
tirzepatide

Month-to-month rate, was $339. Ladder: $249/mo billed $747 quarterly, $229/mo billed $1,374 every 6mo, $199/mo billed $2,388 annually. One-time First Month Special $199. The '$199 per month' figure advertised on /weight-loss is the 12-month prepay rate.

Oral ODT (dissolving tablet), monthly auto-refillCompounded
$229$179/mo
Save 22% right now
semaglutide

Needle-free oral option. Month-to-month, was $279. Ladder: $199 quarterly, $179 every 6mo, $159 annually. First Month Special $179.

Microdose injectable, monthly auto-refillCompounded
$149$119/mo
Save 20% right now
semaglutide

Low-dose line marketed for tolerability. Month-to-month, was $179. Ladder: $129 quarterly, $119 every 6mo, $109 annually. First Month Special $119.

Microdose injectable, monthly auto-refillCompounded
$149$119/mo
Save 20% right now
tirzepatide

Low-dose GLP-1 + GIP. Same ladder as microdose semaglutide: $129 quarterly, $119 every 6mo, $109 annually. First Month Special $119.

Microdose oral ODT, monthly auto-refillCompounded
$179$149/mo
Save 17% right now
semaglutide

Month-to-month, was $209. Ladder: $159 quarterly, $149 every 6mo, $139 annually. First Month Special $149.

PlushCare

StartingCompounded
$149/mo
semaglutide

Range up to $299/mo

StartingCompounded
$399/mo
tirzepatide

Range up to $599/mo

What each price covers

Lttl's price also covers the clinician visit, the medication itself and shipping, which PlushCare does not claim.

Lttl is silent on lab work and coaching.

PlushCare is silent on shipping and coaching.

That matters most for the drug: unless PlushCare confirms otherwise, budget for medication on top of its listed price.

Lttl

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

PlushCare

Covered by the monthly price

Medication

Charged on top

Clinician visits

Charged on top

Shipping

Not stated

Lab work

Charged on top

Coaching

Not stated

Where each one scores higher

Overall, Lttl scores 8.0 and PlushCare 6.4 out of 10.

Lttl is stronger on value (8.7 vs 3.0), user experience (8.0 vs 7.0) and support (7.0 vs 0.0).

PlushCare is stronger on trust & safety (7.5 vs 6.5) and accessibility (10.0 vs 5.0).

Effectiveness is within half a point.

How we score

Lttl

8.0/10

Overall

PlushCare

6.4/10

Value25%

8.7A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
0.0

FDA warning letters

Neither Lttl nor PlushCare has an FDA warning letter on record with us.

Features & Coverage

FeatureLttlPlushCare
Starting Price$149/mo$149/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted✓ Yes—
FDA Warning LettersNoneNone

About Lttl

Prepay for 12 months and compounded semaglutide drops to $129 with tirzepatide at $199; taken month to month they run $199/mo and $279/mo, one flat rate at any dose. Before checkout the entire price matrix is on view, every commitment length, form and medication in it. Longevity peptides and a microdose line at low dose fill out the direct-to-consumer catalog. The name is said aloud as little.

Read our full Lttl review →

About PlushCare

PlushCare is an established virtual primary-care telehealth platform and a subsidiary of Transcarent, Inc., a Delaware corporation that also owns Accolade, 2nd.MD, and 98point6 by Transcarent. Virtual visits with US board-certified physicians cost $30 per appointment insured and $129 self-pay. GLP-1 prescribing is a clinician-discretionary option within the broader primary-care relationship.

Read our full PlushCare review →

Pros & Cons

Lttl

What we like

  • Semaglutide costs $149 a month, 19% below the $184 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $149 a month, 40% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to Lttl

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

PlushCare

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • Serves all 50 states
  • We found no FDA warning letters issued to PlushCare
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Not included in the monthly price: medication, clinician visits, lab work
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Lttl

Lttl wins this one, 8.0 to 6.4, above all for starting below a standard dose, with microdose tiers. PlushCare fits better if coverage in all 50 states, which most sellers will not confirm is your priority.

Choose Lttl if…

You want starting below a standard dose, with microdose tiers and an opening price near $149 a month.

Choose PlushCare if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $149 a month.

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6.5

Sesame Care

Oral orforglipron alongside the injectables

8.4

Collective

Flat any-dose pricing, if you can absorb a $199 annual membership on top

8.6

Found

Tirzepatide at $169/month, 37% below the typical price

Lttl vs PlushCare: FAQ

Neither on the entry price: Lttl and PlushCare both start at about $149 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Lttl does not publish where it ships; PlushCare lists 50 states. Confirm your state before paying.
Only Lttl includes the clinician visit, the medication itself and shipping.
Lttl has none. PlushCare has none.
Lttl pays us a commission on sign-ups through our links; PlushCare does not. Scores are computed the same way for both.

Or see the full category ranking.