He & She MD vs Hello Alpha
An in-depth comparison of two leading GLP-1 Providers
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He & She MD
Best for: starting below a standard dose, with microdose tiers
Visit He & She MD →
Hello Alpha
Best for: seeing what it charges before you answer any medical questions
Visit Hello Alpha →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Hello Alpha opens cheaper — $79/mo against $99, and He & She MD finishes ahead, 9.3 to 6.1. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
He & She MD
⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.
Injectable tirzepatide intro $199/mo (regular $289/mo)
Hello Alpha
$79/month Alpha Plus+ is the weight-loss membership and includes "4 online visits per month"; a $29/month tier includes 2 visits. Medication is billed through insurance or LillyDirect, not the membership.
What’s included
He & She MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Hello Alpha
Covered by the monthly price
Medication
Charged on top
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
He & She MD
9.3/10
Hello Alpha
6.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | He & She MD | Hello Alpha |
|---|---|---|
| Starting Price | $99/mo | ✓$79/mo |
| Features | 8 features | 8 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About He & She MD
GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.
Read our full He & She MD review →About Hello Alpha
Neither a cash price nor a complete state list is spelled out publicly. What Hello Alpha, once called Alpha Medical, does spell out is a wide drug menu: Wegovy, Ozempic, Rybelsus, Zepbound and Mounjaro under their brand names, the oral GLP-1 Foundayo, and further oral weight-loss drugs beyond those. Insurance is part of the model, and an online membership carries ongoing clinician care.
Read our full Hello Alpha review →Pros & Cons
He & She MD
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Hello Alpha
What we like
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers consult and shipping
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Billed separately from the monthly figure: medication
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Our Verdict
He & She MD takes it, 9.3 against 6.1, and it is especially strong on starting below a standard dose, with microdose tiers. Hello Alpha is no weak second and may fit you better on seeing what it charges before you answer any medical questions.
Choose He & She MD if…
You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.
Choose Hello Alpha if…
You want seeing what it charges before you answer any medical questions and an opening price near $79 a month.
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Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Direct Meds
Compounded semaglutide at $249/month
From $249/mo
Get started →Try Ageless
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →He & She MD vs Hello Alpha: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.