Framework vs RxPros
Framework and RxPros both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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Framework
Best for: semaglutide at $100/month, 63% below the typical price
Visit Framework →
If you are choosing between Framework and RxPros, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. They tie at 8.1 on our six-part score.
Framework vs RxPros price
Framework and RxPros start at within a dollar of each other ($100 and $99.99 a month), so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $100 a month; tirzepatide is cheaper at Framework ($100 a month vs $144.97 a month on a prepaid plan).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Neither Framework nor RxPros publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
Framework
RxPros
Lowest tier, requires annual prepay; 3-month shipments. All doses same price; includes doctor visit + overnight shipping.
Lowest tier, requires annual prepay; 3-month shipments. All doses same price; includes doctor visit + shipping.
First-month introductory discount for new patients, or paid quarterly. 'Now only $149' banner price also shown.
First-month introductory discount for new patients, or paid quarterly. 'Now only $249' banner price also shown.
What each price covers
Both prices cover the medication itself.
Framework's price also covers coaching, which RxPros does not claim.
RxPros' price also covers the clinician visit and shipping, which Framework does not claim.
Framework is silent on the clinician visit, shipping and lab work.
RxPros is silent on lab work and coaching.
Framework
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
Not stated
Lab work
Not stated
Coaching
In the price
RxPros
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall they tie at 8.1 out of 10.
Framework is stronger on value (10.0 vs 9.4) and user experience (8.0 vs 7.5).
RxPros is stronger on support (7.0 vs 4.5).
Effectiveness, trust & safety and accessibility are within half a point.
Framework
8.1/10
RxPros
8.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither Framework nor RxPros has an FDA warning letter on record with us.
Features & Coverage
| Feature | Framework | RxPros |
|---|---|---|
| Starting Price | $100/mo | ✓$99.99/mo prepaid |
| Features | 5 features | ✓6 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About Framework
Cost can go as low as $25/week, which is roughly $100/mo; no membership fee applies. A doctor guides which of the compounded drugs, semaglutide or tirzepatide, a patient takes. The detail that stands out is the pharmacy: Framework names The Pharmacy Hub, which works under the FDA-registered 503B outsourcing pathway instead of the patient-specific 503A route nearly every direct-to-consumer competitor relies on.
Read our full Framework review →About RxPros
RxPros LLC is incorporated in Wyoming at 1309 Coffeen Ave Ste 15880, Sheridan, WY 82801, and is LegitScript Certified. Compounded semaglutide is $99.99/month and compounded tirzepatide $144.97/month, but only at the introductory tier paid annually. That covers the doctor visit, medication and overnight cold shipping. Zofran for nausea and B12 are sold as add-ons.
Read our full RxPros review →Pros & Cons
Framework
What we like
- Semaglutide costs $100 a month, 46% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $100 a month, 60% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication and coaching
- We found no FDA warning letters issued to Framework
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
RxPros
What we like
- Semaglutide costs $99.99 a month, 46% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $144.97 a month, 42% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to RxPros
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Framework and RxPros finish level at 8.1. Choose on the state list and on what each monthly price covers.
Choose Framework if…
You want semaglutide at $100/month, 63% below the typical price and an opening price near $100 a month.
Choose RxPros if…
You want semaglutide at $99.99/month, 47% below the typical price and an opening price near $99.99 a month.
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RxSpan MD
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $249/mo
Get started →Luvo Health
Moving between compounded and brand without changing seller
From $249/mo
Get started →Strut Health
Semaglutide at $99/month, 48% below the typical price
From $99/mo
Get started →Framework vs RxPros: FAQ
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