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Fierce Health vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Fierce Health logo

Fierce Health

6.7
★★★☆☆3.4/5

Best for: starting below a standard dose, with microdose tiers

Visit Fierce Health
VS
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $197, and He & She MD finishes ahead, 9.3 to 6.7. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

Fierce Health

Semaglutide Weight Loss Program, monthlyCompounded
$297/mo
semaglutide

Also sold as 3-month and 6-month paid-in-full cadences. Free US shipping.

Tirzepatide Weight Loss Program, monthlyCompounded
$497/mo
tirzepatide

Also sold as 3-month and 6-month paid-in-full cadences.

Semaglutide Microdose Program, monthly (low-dose protocol)Compounded
$197/mo
semaglutide

Listed as "From $197.00"; one vial per month.

Tirzepatide Microdose Program, monthly (low-dose protocol)Compounded
$297/mo
tirzepatide

Listed as "From $297.00"; one vial per month.

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

What’s included

Fierce Health

Covered by the monthly price

Medication

Not stated

Clinician visits

Not stated

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Fierce Health

6.7/10

Overall

He & She MD

9.3/10

Value25%

4.7A
vs
B
9.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

4.5A
vs
B
8.5

Accessibility10%

6.8A
vs
B
10.0

Support10%

5.0A
vs
B
8.5

Features & Coverage

FeatureFierce HealthHe & She MD
Starting Price$197/mo$99/mo
Features5 features8 features
States Available3050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings5 warningsNone

About Fierce Health

Fierce Health prices its GLP-1 programs at $197-$497/mo. It sells compounded semaglutide and tirzepatide in both standard and microdose programs, a four-program ladder broader than peers selling only one or two SKUs, with the microdose tier among the lower entry points. A longevity catalog sits alongside it. Service is limited to 30 enumerated states, and the platform is LegitScript Certified.

Read our full Fierce Health review →

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

Pros & Cons

Fierce Health

What we like

  • Semaglutide at $197 a month, within the normal band around this register's $189 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers shipping

Watch-outs

  • Coverage is published for 30 states only, so this may not reach you
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • 5 FDA warning letters matched to this operator in our enforcement register — read what the letter alleges, since a letter discloses a problem rather than disqualifying a seller
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 6.7, and it is especially strong on starting below a standard dose, with microdose tiers. Fierce Health is no weak second and may fit you better on starting below a standard dose, with microdose tiers.

Choose Fierce Health if…

You want starting below a standard dose, with microdose tiers and an opening price near $197 a month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

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7.9

Oak

Semaglutide at $119/month, 37% under the register median

6.5

Direct Meds

Compounded semaglutide at $249/month

7.7

Try Ageless

Semaglutide at $119/month, 37% under the register median

Fierce Health vs He & She MD: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.