DudeMeds vs TrimRx
DudeMeds costs $4 less a month, and both sell semaglutide and tirzepatide.
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If you are choosing between DudeMeds and TrimRx, the first difference is cost: DudeMeds is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. TrimRx leads our six-part score, 7.2 to 6.1.
DudeMeds vs TrimRx price
DudeMeds is the cheaper way in: $175 a month on a prepaid plan against $179 a month at TrimRx. That is $4 less each month (2% lower), or about $48 over a year of treatment.
DudeMeds' figure is a monthly average of a plan billed for several months at once, so the first charge is larger than the number shown.
Drug by drug: Semaglutide is cheaper at DudeMeds ($175 a month on a prepaid plan vs $179 a month); tirzepatide is cheaper at DudeMeds ($233 a month vs $259 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and brand-name pens.
Where each one treats patients
Neither DudeMeds nor TrimRx publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
DudeMeds
$175/mo (orig $295 struck), Total Billed $525 (Orig. $885); 503B compounded; cheapest product on site — advertised '$149+' price not found on any product page
$179/mo (orig $295), Total Billed $716 (Orig. $1,180)
$597 billed (orig $885); ongoing refill tier
$498 billed (orig $590); ongoing refill tier
$837 billed (orig $885); ongoing refill tier
$249/mo, billed as $747 up front (shown against a struck-through $1,299).
$699 billed (orig $1,299); ongoing refill tier — below the $249 tirz median
$598 billed (orig $866); ongoing refill tier
$1,179 billed (orig $1,299); NOTE site labels this 'High Dose' at 5mg/week — same mg as the low tier, likely a site labeling error
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,050 (3 months)
NEW branch: Total Billed $4,050 (3 months)
TrimRx
GLP-1 starts at $179. The homepage shows a $299.00 list price struck through to $179.00 for the first month, and an email sign-up offer promises '$120 OFF' your first order, for a first month as low as $135. Multi-month bundles (formerly $209/$191/$174) are no longer published; plan prices appear only after the intake questionnaire.
The GLP-1 + GIP plan, which contains tirzepatide, starts at $259, down from an earlier $279 limited offer. Multi-month bundles (formerly $316/$299/$283) are no longer published; plan prices appear only after the intake questionnaire.
'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
DudeMeds is silent on lab work and coaching.
TrimRx is silent on lab work and coaching.
DudeMeds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
TrimRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, TrimRx scores 7.2 and DudeMeds 6.1 out of 10.
TrimRx is stronger on user experience (8.0 vs 3.0) and trust & safety (6.5 vs 4.0).
Value, effectiveness, accessibility and support are within half a point.
DudeMeds
6.1/10
TrimRx
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither DudeMeds nor TrimRx has an FDA warning letter on record with us.
Features & Coverage
| Feature | DudeMeds | TrimRx |
|---|---|---|
| Starting Price | ✓$175/mo prepaid | $179/mo |
| Features | 4 features | ✓8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About DudeMeds
Semaglutide and tirzepatide start at $175/month, sold in injectable and oral formats alike, with free shipping, no doctor fee and no membership fee. DudeMeds is a telehealth platform for men that also sells hair loss, ED and TRT treatments, and it accepts clinic-switch patients who come from an existing GLP-1 and TRT provider.
Read our full DudeMeds review →About TrimRx
Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.
Read our full TrimRx review →Pros & Cons
DudeMeds
What we like
- Semaglutide costs $175 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $233 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to DudeMeds
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
TrimRx
What we like
- Semaglutide costs $179 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $259 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to TrimRx
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
DudeMeds is where we would start, above all for compounded semaglutide at $175/month. It also costs $4 less each month than TrimRx. TrimRx fits better if compounded semaglutide at $179/month is your priority.
Choose DudeMeds if…
You want compounded semaglutide at $175/month and an opening price near $175 a month.
Choose TrimRx if…
You want compounded semaglutide at $179/month and an opening price near $179 a month.
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He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →DudeMeds vs TrimRx: FAQ
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Or see the full category ranking.
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