DudeMeds vs Vaylen
DudeMeds costs $4 less a month, and both sell semaglutide and tirzepatide.
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Vaylen
Best for: bloodwork inside the $179/month rather than billed on top
Visit Vaylen →If you are choosing between DudeMeds and Vaylen, the first difference is cost: DudeMeds is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Vaylen leads our six-part score, 8.2 to 6.1.
DudeMeds vs Vaylen price
DudeMeds is the cheaper way in: $175 a month on a prepaid plan against $179 a month at Vaylen. That is $4 less each month (2% lower), or about $48 over a year of treatment.
DudeMeds' figure is a monthly average of a plan billed for several months at once, so the first charge is larger than the number shown.
Drug by drug: Semaglutide is cheaper at DudeMeds ($175 a month on a prepaid plan vs $179 a month); tirzepatide is cheaper at DudeMeds ($233 a month vs $239 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and brand-name pens.
Where each one treats patients
DudeMeds does not publish where it ships, and Vaylen lists 50 states.
Pricing
DudeMeds
$175/mo (orig $295 struck), Total Billed $525 (Orig. $885); 503B compounded; cheapest product on site — advertised '$149+' price not found on any product page
$179/mo (orig $295), Total Billed $716 (Orig. $1,180)
$597 billed (orig $885); ongoing refill tier
$498 billed (orig $590); ongoing refill tier
$837 billed (orig $885); ongoing refill tier
$249/mo, billed as $747 up front (shown against a struck-through $1,299).
$699 billed (orig $1,299); ongoing refill tier — below the $249 tirz median
$598 billed (orig $866); ongoing refill tier
$1,179 billed (orig $1,299); NOTE site labels this 'High Dose' at 5mg/week — same mg as the low tier, likely a site labeling error
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,050 (3 months)
NEW branch: Total Billed $4,050 (3 months)
Vaylen
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
Vaylen's price also covers lab work and coaching, which DudeMeds does not claim.
DudeMeds is silent on lab work and coaching.
DudeMeds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Vaylen
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
In the price
Coaching
In the price
Where each one scores higher
Overall, Vaylen scores 8.2 and DudeMeds 6.1 out of 10.
Vaylen is stronger on user experience (7.5 vs 3.0), trust & safety (8.5 vs 4.0), accessibility (10.0 vs 5.0) and support (10.0 vs 7.0).
Value and effectiveness are within half a point.
DudeMeds
6.1/10
Vaylen
8.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither DudeMeds nor Vaylen has an FDA warning letter on record with us.
Features & Coverage
| Feature | DudeMeds | Vaylen |
|---|---|---|
| Starting Price | ✓$175/mo prepaid | $179/mo |
| Features | 4 features | ✓8 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About DudeMeds
Semaglutide and tirzepatide start at $175/month, sold in injectable and oral formats alike, with free shipping, no doctor fee and no membership fee. DudeMeds is a telehealth platform for men that also sells hair loss, ED and TRT treatments, and it accepts clinic-switch patients who come from an existing GLP-1 and TRT provider.
Read our full DudeMeds review →About Vaylen
Vaylen is a pure GLP-1 specialist: compounded semaglutide at $179/mo, compounded tirzepatide at $239/mo, a compounded oral GLP-1 at $259/mo, and brand-name Ozempic, Zepbound, and Wegovy. LegitScript certified, with licensed clinicians in all 50 states.
Read our full Vaylen review →Pros & Cons
DudeMeds
What we like
- Semaglutide costs $175 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $233 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to DudeMeds
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Vaylen
What we like
- Semaglutide costs $179 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $239 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits, shipping, lab work and coaching
- Serves all 50 states
- We found no FDA warning letters issued to Vaylen
- Baseline bloodwork is required before a prescription
Watch-outs
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
DudeMeds is where we would start, above all for compounded semaglutide at $175/month. It also costs $4 less each month than Vaylen. Vaylen fits better if bloodwork inside the $179/month rather than billed on top is your priority.
Choose DudeMeds if…
You want compounded semaglutide at $175/month and an opening price near $175 a month.
Choose Vaylen if…
You want bloodwork inside the $179/month rather than billed on top and an opening price near $179 a month.
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Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →DudeMeds vs Vaylen: FAQ
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.