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Calibrate Health vs TrimRx

Calibrate Health and TrimRx sell different medications; this is what separates them.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Calibrate Health logo

Calibrate Health

6.7
★★★☆☆3.4/5

Best for: coaching bundled into the price rather than sold separately

Visit Calibrate Health →
VS
TrimRx logo

TrimRx

6.3
★★★☆☆3.2/5

Best for: compounded semaglutide at $299/month after a $199 first month

Visit TrimRx →

If you are choosing between Calibrate Health and TrimRx, price alone will not settle it. Calibrate Health leads our six-part score, 6.7 to 6.3.

Calibrate Health vs TrimRx price

TrimRx publishes $299 a month. Calibrate Health does not post a GLP-1 price we can quote, so you would only learn its cost after an intake.

Medications and formats

TrimRx lists semaglutide and tirzepatide; Calibrate Health does not name its drug.

On format, Calibrate Health posts no priced format, while TrimRx prices compounded injections and brand-name pens.

If you want the FDA-approved brand rather than a compounded version, TrimRx is the only one of the two with a brand-name price.

Where each one treats patients

Calibrate Health lists 50 states, and TrimRx does not publish where it ships.

Pricing

Calibrate Health

Metabolic Reset membership program fee (initial 3-month commitment)Brand-name
$199/mo
semaglutide

$199/mo membership program fee; $597 total over the initial 3-month commitment, billed in monthly installments; renews monthly after; medication billed separately

Medication copay with commercial insurance + savings cardBrand-name
$25/mo
semaglutide

typically $25/mo or less with insurance after any deductible; on top of the $199/mo program fee

TrimRx

GLP-1 (semaglutide) monthly planCompounded
$299$199/mo
Save 33% right now
semaglutide

TrimRx's terms price the first month at $199 and each follow-up month at $299, with medication, consultation and shipping included. The home page advertises 'Starting at $179', which the terms do not tie to a month-to-month plan.

GLP-1 + GIP (tirzepatide) monthly planCompounded
$399$349/mo
Save 13% right now
tirzepatide

TrimRx's terms price the first month at $349 and each follow-up month at $399, with medication, consultation and shipping included. The home page advertises 'Starting at $259', which the terms do not tie to a month-to-month plan.

Ozempic monthly planBrand-name
$1299/mo
semaglutide (ozempic)

Priced at $1,299 for the first month and $1,299 for follow-up months, medication included.

Zepbound monthly planBrand-name
$1399/mo
tirzepatide (zepbound)

Priced at $1,399 for the first month and $1,399 for follow-up months, medication included.

What each price covers

Both prices cover the clinician visit.

Calibrate Health's price also covers coaching, which TrimRx does not claim.

TrimRx's price also covers the medication itself and shipping, which Calibrate Health does not claim.

Calibrate Health is silent on shipping and lab work.

TrimRx is silent on lab work and coaching.

That matters most for the drug: unless Calibrate Health confirms otherwise, budget for medication on top of its listed price.

Calibrate Health

Covered by the monthly price

Medication

Charged on top

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

In the price

TrimRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Calibrate Health scores 6.7 and TrimRx 6.3 out of 10.

Calibrate Health is stronger on value (3.0 vs 1.6), trust & safety (8.5 vs 6.5) and accessibility (10.0 vs 5.0).

TrimRx is stronger on effectiveness (10.0 vs 9.0), user experience (8.0 vs 7.0) and support (7.0 vs 4.0).

How we score

Calibrate Health

6.7/10

Overall

TrimRx

6.3/10

Value25%

3.0A
vs
B
1.6

Effectiveness25%

9.0A
vs
B
10.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

8.5A
vs
B
6.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

4.0A
vs
B
7.0

FDA warning letters

Neither Calibrate Health nor TrimRx has an FDA warning letter on record with us.

Features & Coverage

FeatureCalibrate HealthTrimRx
Starting PriceNot published$299/mo
Features8 features8 features
States Available50Not disclosed
Compounded—✓ Yes
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Calibrate Health

The program fee is $199/month and it buys no medication; the drug is billed apart and, with insurance plus a savings card, can fall to roughly $25/month. Calibrate runs a full year as a metabolic reset, pairing a branded GLP-1 drug, Wegovy, Ozempic, Zepbound or Foundayo, with video coaching one-to-one and dietitian support. That is a heavier clinical wrap than transactional telehealth offers. Only branded drugs are used, and outcomes carry a money-back guarantee.

Read our full Calibrate Health review →

About TrimRx

Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.

Read our full TrimRx review →

Pros & Cons

Calibrate Health

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes clinician visits and coaching
  • Serves all 50 states
  • We found no FDA warning letters issued to Calibrate Health
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Not included in the monthly price: medication
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

TrimRx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to TrimRx

Watch-outs

  • Semaglutide costs $299 a month, 62% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $399 a month, 60% above the $250 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Calibrate Health

Calibrate Health wins this one, 6.7 to 6.3, above all for coaching bundled into the price rather than sold separately. TrimRx fits better if compounded semaglutide at $299/month after a $199 first month is your priority.

Choose Calibrate Health if…

You want coaching bundled into the price rather than sold separately.

Choose TrimRx if…

You want compounded semaglutide at $299/month after a $199 first month and an opening price near $299 a month.

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9.0

bmiMD

Starting below a standard dose, with microdose tiers

6.7

RxSpan MD

Knowing which pharmacy fills the vial: it names Belmar Pharmacy

6.6

Luvo Health

Moving between compounded and brand without changing seller

Calibrate Health vs TrimRx: FAQ

Only TrimRx publishes a price ($299 a month). Calibrate Health quotes after sign-up.
No. Calibrate Health lists no named drug; TrimRx lists semaglutide and tirzepatide.
Calibrate Health lists 50 states; TrimRx does not publish where it ships. Confirm your state before paying.
Both include the clinician visit. Only Calibrate Health includes coaching. Only TrimRx includes the medication itself and shipping.
Calibrate Health has none. TrimRx has none.
No. Neither Calibrate Health nor TrimRx pays us anything.

Or see the full category ranking.

Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.