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Brello Health vs Piper

Piper costs $22.72 less a month, and both sell semaglutide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Brello Health logo

Brello Health

7.4
★★★★☆3.7/5

Best for: seeing what it charges before you answer any medical questions

Visit Brello Health →
VS
Piper logo

Piper

7.4
★★★★☆3.7/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit Piper →

If you are choosing between Brello Health and Piper, the first difference is cost: Piper is $22.72 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. They tie at 7.4 on our six-part score.

Brello Health vs Piper price

Piper is the cheaper way in: $135 a month against $157.72 a month at Brello Health. That is $22.72 less each month (14% lower), or about $272.64 over a year of treatment.

Drug by drug: Semaglutide is cheaper at Piper ($135 a month vs $157.72 a month).

Medications and formats

Both sell semaglutide; only Piper lists tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Brello Health lists 35 states, and Piper lists 50 states.

They overlap in 34 states. Brello Health alone covers District of Columbia. Piper alone covers 16 states, including Alabama, Arkansas, California and Connecticut.

Pricing

Brello Health

Compounded semaglutide, billed $399 every 11 weeksCompounded
$157.72/mo
semaglutide

Piper

StartingCompounded
$135/mo
semaglutide
StartingCompounded
$199/mo
tirzepatide

What each price covers

Both prices cover the clinician visit and the medication itself.

Piper's price also covers shipping, which Brello Health does not claim.

Brello Health is silent on shipping, lab work and coaching.

Piper is silent on lab work and coaching.

Brello Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

Piper

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall they tie at 7.4 out of 10.

Brello Health is stronger on value (6.1 vs 3.0).

Piper is stronger on effectiveness (10.0 vs 8.5), accessibility (10.0 vs 7.6) and support (7.0 vs 5.5).

User experience and trust & safety are within half a point.

How we score

Brello Health

7.4/10

Overall

Piper

7.4/10

Value25%

6.1A
vs
B
3.0

Effectiveness25%

8.5A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.5A
vs
B
8.5

Accessibility10%

7.6A
vs
B
10.0

Support10%

5.5A
vs
B
7.0

FDA warning letters

Neither Brello Health nor Piper has an FDA warning letter on record with us.

Features & Coverage

FeatureBrello HealthPiper
Starting Price$157.72/mo✓$135/mo
Features2 features✓3 features
States Available35✓50
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Brello Health

Brello Health is a telehealth wellness platform selling GLP-1 weight management.

Read our full Brello Health review →

About Piper

Piper is a telehealth weight loss seller offering compounded GLP-1 medications at competitive prices.

Read our full Piper review →

Pros & Cons

Brello Health

What we like

  • Semaglutide costs $157.72 a month, 14% below the $184 median for compounded semaglutide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to Brello Health

Watch-outs

  • Serves only 35 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Piper

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to Piper

Watch-outs

  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Brello Health and Piper finish level at 7.4. Piper is $22.72 a month cheaper, which makes it the default unless the other covers your state and it does not.

Choose Brello Health if…

You want seeing what it charges before you answer any medical questions and an opening price near $157.72 a month.

Choose Piper if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $135 a month.

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7.3

RNK Health

An oral route if you will not self-inject

9.2

He & She MD

Starting below a standard dose, with microdose tiers

5.9

Wellorithm

Compounded semaglutide at $247/month

Brello Health vs Piper: FAQ

Piper. It starts at $135 a month; Brello Health starts at $157.72 a month, $22.72 more per month.
Yes, both sell semaglutide. Piper adds tirzepatide.
Piper: 50 states against 35, with 34 in common.
Both include the clinician visit and the medication itself. Only Piper includes shipping.
Brello Health has none. Piper has none.
No. Neither Brello Health nor Piper pays us anything.

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