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Brello Health vs SynergenX Health

SynergenX Health costs $7.72 less a month, and both sell semaglutide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Brello Health logo

Brello Health

7.4
★★★★☆3.7/5

Best for: seeing what it charges before you answer any medical questions

Visit Brello Health →
VS
SynergenX Health logo

SynergenX Health

5.1
★★★☆☆2.6/5

Best for: a published list of the 10 states it serves, when most sellers publish none

Visit SynergenX Health →

If you are choosing between Brello Health and SynergenX Health, the first difference is cost: SynergenX Health is $7.72 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. Brello Health leads our six-part score, 7.4 to 5.1.

Brello Health vs SynergenX Health price

SynergenX Health is the cheaper way in: $150 a month against $157.72 a month at Brello Health. That is $7.72 less each month (5% lower), or about $92.64 over a year of treatment.

Drug by drug: Semaglutide is cheaper at SynergenX Health ($150 a month vs $157.72 a month).

Medications and formats

Both sell semaglutide.

On format they match: each offers compounded injections.

Where each one treats patients

Brello Health lists 35 states, and SynergenX Health lists 10 states.

They overlap in 6 states. Brello Health alone covers 29 states, including Alaska, Arizona, District of Columbia and Delaware. SynergenX Health alone covers Arkansas, Indiana, North Carolina and Tennessee.

Pricing

Brello Health

Compounded semaglutide, billed $399 every 11 weeksCompounded
$157.72/mo
semaglutide

SynergenX Health

Starting doseCompounded
$150/mo
semaglutide

Compounded semaglutide 'starts as low as $150 for one month of treatment,' medication included. The first telehealth consult ($100) and follow-up visits ($40 each, every 1–3 months) are billed separately. Prices at higher doses are not published.

What each price covers

Both prices cover the clinician visit and the medication itself.

SynergenX Health's price also covers shipping, which Brello Health does not claim.

Brello Health is silent on shipping, lab work and coaching.

Brello Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

SynergenX Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Charged on top

Coaching

Charged on top

Where each one scores higher

Overall, Brello Health scores 7.4 and SynergenX Health 5.1 out of 10.

Brello Health is stronger on value (6.1 vs 3.0), user experience (8.0 vs 2.5), trust & safety (8.5 vs 5.0) and accessibility (7.6 vs 3.6).

SynergenX Health is stronger on support (7.0 vs 5.5).

Effectiveness is within half a point.

How we score

Brello Health

7.4/10

Overall

SynergenX Health

5.1/10

Value25%

6.1A
vs
B
3.0

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

8.0A
vs
B
2.5

Trust & Safety15%

8.5A
vs
B
5.0

Accessibility10%

7.6A
vs
B
3.6

Support10%

5.5A
vs
B
7.0

FDA warning letters

Neither Brello Health nor SynergenX Health has an FDA warning letter on record with us.

Features & Coverage

FeatureBrello HealthSynergenX Health
Starting Price$157.72/mo✓$150/mo
Features2 features✓8 features
States Available✓3510
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Brello Health

Brello Health is a telehealth wellness platform selling GLP-1 weight management.

Read our full Brello Health review →

About SynergenX Health

A telehealth consultation at $100 comes first. After it, compounded semaglutide opens at $150/month with refrigerated shipping to the home and the drug both covered, and follow-ups cost $40 at intervals of 1-3 months. Texas patients are the only ones who can use the online program at present, though the chain itself spans 64 locations over 10 states doing hormone and weight-loss work. Counseling on nutrition and lifestyle, clinical support that continues, and dosing set for the individual are part of treatment.

Read our full SynergenX Health review →

Pros & Cons

Brello Health

What we like

  • Semaglutide costs $157.72 a month, 14% below the $184 median for compounded semaglutide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to Brello Health

Watch-outs

  • Serves only 35 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

SynergenX Health

What we like

  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to SynergenX Health
  • Baseline bloodwork is required before a prescription

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Not included in the monthly price: lab work, coaching
  • Serves only 10 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Brello Health

Brello Health wins this one, 7.4 to 5.1, above all for seeing what it charges before you answer any medical questions. SynergenX Health undercuts it by $7.72 a month, so if the monthly bill is what decides it, SynergenX Health is the pick. SynergenX Health fits better if a published list of the 10 states it serves, when most sellers publish none is your priority.

Choose Brello Health if…

You want seeing what it charges before you answer any medical questions and an opening price near $157.72 a month.

Choose SynergenX Health if…

You want a published list of the 10 states it serves, when most sellers publish none and an opening price near $150 a month.

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5.9

Wellorithm

Compounded semaglutide at $247/month

6.6

Willow

Seeing what it charges before you answer any medical questions

6.5

Sesame Care

Oral orforglipron alongside the injectables

Brello Health vs SynergenX Health: FAQ

SynergenX Health. It starts at $150 a month; Brello Health starts at $157.72 a month, $7.72 more per month.
Yes, both sell semaglutide.
Brello Health: 35 states against 10, with 6 in common.
Both include the clinician visit and the medication itself. Only SynergenX Health includes shipping.
Brello Health has none. SynergenX Health has none.
No. Neither Brello Health nor SynergenX Health pays us anything.

Or see the full category ranking.