AM Rx vs SynergenX Health
SynergenX Health costs $1 less a month, and both sell semaglutide.
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SynergenX Health
Best for: a published list of the 10 states it serves, when most sellers publish none
Visit SynergenX Health →If you are choosing between AM Rx and SynergenX Health, the first difference is cost: SynergenX Health is $1 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. AM Rx leads our six-part score, 5.4 to 5.1. One of the two has an FDA warning letter on record, covered below.
AM Rx vs SynergenX Health price
SynergenX Health is the cheaper way in: $150 a month against $151 a month on a prepaid plan at AM Rx. That is $1 less each month (1% lower), or about $12 over a year of treatment.
AM Rx's figure is a monthly average of a plan billed for several months at once, so the first charge is larger than the number shown.
Drug by drug: Semaglutide is cheaper at SynergenX Health ($150 a month vs $151 a month on a prepaid plan).
Medications and formats
Both sell semaglutide.
On format they match: each offers compounded injections.
Where each one treats patients
AM Rx does not publish where it ships, and SynergenX Health lists 10 states.
Pricing
AM Rx
As low as $25/mo with insurance coordination; a separate AM Rx membership is still required.
Medication only ($151/mo when purchased quarterly); the recurring AM Rx membership is billed on top.
Standard $135/mo membership, $39 first month ($96 off promo); renews monthly. Medication is billed separately. drug omitted intentionally.
SynergenX Health
Compounded semaglutide 'starts as low as $150 for one month of treatment,' medication included. The first telehealth consult ($100) and follow-up visits ($40 each, every 1–3 months) are billed separately. Prices at higher doses are not published.
What each price covers
SynergenX Health's price also covers the clinician visit, the medication itself and shipping, which AM Rx does not claim.
AM Rx does not say what its price includes.
That matters most for the drug: unless AM Rx confirms otherwise, budget for medication on top of its listed price.
AM Rx
Inclusions not disclosed.
SynergenX Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Charged on top
Coaching
Charged on top
Where each one scores higher
Overall, AM Rx scores 5.4 and SynergenX Health 5.1 out of 10.
AM Rx is stronger on value (6.4 vs 3.0), effectiveness (9.0 vs 8.5) and accessibility (5.0 vs 3.6).
SynergenX Health is stronger on trust & safety (5.0 vs 1.0) and support (7.0 vs 5.0).
User experience is within half a point.
AM Rx
5.4/10
SynergenX Health
5.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent AM Rx a warning letter dated June 8, 2026 (letter 728275), and it is still open.
SynergenX Health has no FDA warning letter on record with us.
Features & Coverage
| Feature | AM Rx | SynergenX Health |
|---|---|---|
| Starting Price | $151/mo prepaid | ✓$150/mo |
| Features | 7 features | ✓8 features |
| States Available | Not disclosed | 10 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 3 letters | ✓None |
About AM Rx
AM Rx is a telehealth platform operated by FitRX, LLC, which also operates Zealthy and FitRx. Compounded semaglutide starts at $151/mo on a quarterly plan, and brand-name GLP-1s, Ozempic, Wegovy, Zepbound, and Mounjaro, come with insurance coordination as low as $25/mo. Consultations can be video or async. HSA/FSA accepted.
Read our full AM Rx review →About SynergenX Health
A telehealth consultation at $100 comes first. After it, compounded semaglutide opens at $150/month with refrigerated shipping to the home and the drug both covered, and follow-ups cost $40 at intervals of 1-3 months. Texas patients are the only ones who can use the online program at present, though the chain itself spans 64 locations over 10 states doing hormone and weight-loss work. Counseling on nutrition and lifestyle, clinical support that continues, and dosing set for the individual are part of treatment.
Read our full SynergenX Health review →Pros & Cons
AM Rx
What we like
- Semaglutide costs $151 a month, 18% below the $184 median for compounded semaglutide across the sellers we compare
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued AM Rx 3 warning letters. Read what they allege: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
SynergenX Health
What we like
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to SynergenX Health
- Baseline bloodwork is required before a prescription
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: lab work, coaching
- Serves only 10 states, so check that yours is one of them
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
AM Rx wins this one, 5.4 to 5.1, above all for compounded semaglutide at $151/month. SynergenX Health undercuts it by $1 a month, so if the monthly bill is what decides it, SynergenX Health is the pick. SynergenX Health fits better if a published list of the 10 states it serves, when most sellers publish none is your priority.
Choose AM Rx if…
You want compounded semaglutide at $151/month and an opening price near $151 a month.
Choose SynergenX Health if…
You want a published list of the 10 states it serves, when most sellers publish none and an opening price near $150 a month.
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Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →RNK Health
An oral route if you will not self-inject
From $197/mo
Get started →AM Rx vs SynergenX Health: FAQ
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