FitRx vs SynergenX Health
SynergenX Health costs $1 less a month, and both sell semaglutide.
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FitRx
Best for: coverage in all 50 states, which most sellers will not confirm
Visit FitRx →
SynergenX Health
Best for: a published list of the 10 states it serves, when most sellers publish none
Visit SynergenX Health →If you are choosing between FitRx and SynergenX Health, the first difference is cost: SynergenX Health is $1 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. FitRx leads our six-part score, 7.6 to 5.1. One of the two has an FDA warning letter on record, covered below.
FitRx vs SynergenX Health price
SynergenX Health is the cheaper way in: $150 a month against $151 a month on a prepaid plan at FitRx. That is $1 less each month (1% lower), or about $12 over a year of treatment.
FitRx's figure is a monthly average of a plan billed for several months at once, so the first charge is larger than the number shown.
Drug by drug: Semaglutide is cheaper at SynergenX Health ($150 a month vs $151 a month on a prepaid plan).
Medications and formats
Both sell semaglutide.
On format they match: each offers compounded injections.
Where each one treats patients
FitRx lists 51 states, and SynergenX Health lists 10 states.
They overlap in 10 states. FitRx alone covers 41 states, including Alaska, Alabama, Arizona and California.
Pricing
FitRx
With insurance coordination
SynergenX Health
Compounded semaglutide 'starts as low as $150 for one month of treatment,' medication included. The first telehealth consult ($100) and follow-up visits ($40 each, every 1–3 months) are billed separately. Prices at higher doses are not published.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
FitRx is silent on lab work and coaching.
FitRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
SynergenX Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Charged on top
Coaching
Charged on top
Where each one scores higher
Overall, FitRx scores 7.6 and SynergenX Health 5.1 out of 10.
FitRx is stronger on value (6.4 vs 3.0), effectiveness (9.0 vs 8.5), user experience (8.0 vs 2.5), trust & safety (5.5 vs 5.0) and accessibility (10.0 vs 3.6).
Support is within half a point.
FitRx
7.6/10
SynergenX Health
5.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent FitRx a warning letter dated February 20, 2026 (letter 717987), and it is still open.
SynergenX Health has no FDA warning letter on record with us.
Features & Coverage
| Feature | FitRx | SynergenX Health |
|---|---|---|
| Starting Price | $151/mo prepaid | ✓$150/mo |
| Features | 8 features | 8 features |
| States Available | ✓51 | 10 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About FitRx
Insurance coordination at FitRx can bring brand-name GLP-1s down to $25/month, and four are on offer: Mounjaro, Zepbound, Wegovy, and Ozempic. Skip insurance and compounded semaglutide starts at $151/month. DC and all 50 states are covered, and the platform holds LegitScript certification.
Read our full FitRx review →About SynergenX Health
A telehealth consultation at $100 comes first. After it, compounded semaglutide opens at $150/month with refrigerated shipping to the home and the drug both covered, and follow-ups cost $40 at intervals of 1-3 months. Texas patients are the only ones who can use the online program at present, though the chain itself spans 64 locations over 10 states doing hormone and weight-loss work. Counseling on nutrition and lifestyle, clinical support that continues, and dosing set for the individual are part of treatment.
Read our full SynergenX Health review →Pros & Cons
FitRx
What we like
- Semaglutide costs $151 a month, 18% below the $184 median for compounded semaglutide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
Watch-outs
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued FitRx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
SynergenX Health
What we like
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to SynergenX Health
- Baseline bloodwork is required before a prescription
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: lab work, coaching
- Serves only 10 states, so check that yours is one of them
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
FitRx wins this one, 7.6 to 5.1, above all for coverage in all 50 states, which most sellers will not confirm. SynergenX Health undercuts it by $1 a month, so if the monthly bill is what decides it, SynergenX Health is the pick. SynergenX Health fits better if a published list of the 10 states it serves, when most sellers publish none is your priority.
Choose FitRx if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $151 a month.
Choose SynergenX Health if…
You want a published list of the 10 states it serves, when most sellers publish none and an opening price near $150 a month.
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