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Apex MD vs TrimRx

Apex MD and TrimRx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed

Apex MD

7.0
★★★★☆3.5/5

Best for: an oral route if you will not self-inject

Visit Apex MD →
VS
TrimRx logo

TrimRx

6.3
★★★☆☆3.2/5

Best for: compounded semaglutide at $299/month after a $199 first month

Visit TrimRx →

If you are choosing between Apex MD and TrimRx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Apex MD leads our six-part score, 7.0 to 6.3.

Apex MD vs TrimRx price

Apex MD and TrimRx start at the same figure, $299 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $299 a month; tirzepatide costs the same at both, $399 a month.

Medications and formats

Both sell semaglutide and tirzepatide.

On format, Apex MD prices compounded injections, while TrimRx prices compounded injections and brand-name pens.

If you want the FDA-approved brand rather than a compounded version, TrimRx is the only one of the two with a brand-name price.

Where each one treats patients

Apex MD lists 51 states, and TrimRx does not publish where it ships.

Pricing

Apex MD

All doses (injection)Compounded
$299/mo
semaglutide

weekly injection, includes NAD/B-12/L-Carnitine, month-to-month

All doses (injection)Compounded
$399/mo
tirzepatide

weekly injection, month-to-month

All doses (oral)Compounded
$349/mo
semaglutide

daily oral

All doses (oral)Compounded
$419/mo
tirzepatide

daily oral

TrimRx

GLP-1 (semaglutide) monthly planCompounded
$299$199/mo
Save 33% right now
semaglutide

TrimRx's terms price the first month at $199 and each follow-up month at $299, with medication, consultation and shipping included. The home page advertises 'Starting at $179', which the terms do not tie to a month-to-month plan.

GLP-1 + GIP (tirzepatide) monthly planCompounded
$399$349/mo
Save 13% right now
tirzepatide

TrimRx's terms price the first month at $349 and each follow-up month at $399, with medication, consultation and shipping included. The home page advertises 'Starting at $259', which the terms do not tie to a month-to-month plan.

Ozempic monthly planBrand-name
$1299/mo
semaglutide (ozempic)

Priced at $1,299 for the first month and $1,299 for follow-up months, medication included.

Zepbound monthly planBrand-name
$1399/mo
tirzepatide (zepbound)

Priced at $1,399 for the first month and $1,399 for follow-up months, medication included.

What each price covers

Both prices cover the clinician visit, the medication itself and shipping.

Apex MD is silent on lab work and coaching.

TrimRx is silent on lab work and coaching.

Apex MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

TrimRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Apex MD scores 7.0 and TrimRx 6.3 out of 10.

Apex MD is stronger on trust & safety (8.5 vs 6.5) and accessibility (10.0 vs 5.0).

TrimRx is stronger on user experience (8.0 vs 7.5).

Value, effectiveness and support are within half a point.

How we score

Apex MD

7.0/10

Overall

TrimRx

6.3/10

Value25%

1.6A
vs
B
1.6

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

8.5A
vs
B
6.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

FDA warning letters

Neither Apex MD nor TrimRx has an FDA warning letter on record with us.

Features & Coverage

FeatureApex MDTrimRx
Starting Price$299/mo$299/mo
Features8 features8 features
States Available51Not disclosed
Compounded✓ Yes✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Apex MD

By injection each week: 299 dollars per month covers compounded semaglutide, 399 dollars compounded tirzepatide. Swallowed daily instead, semaglutide is 349 dollars per month and tirzepatide 419 dollars. L-Carnitine, B-12 and NAD are added into the formulations. No extra fee attaches to Labcorp labs or to provider visits, of which there is no limit, and the package usually arrives inside four business days. Microdosing is on the menu, and licensure covers all 50 states.

Read our full Apex MD review →

About TrimRx

Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.

Read our full TrimRx review →

Pros & Cons

Apex MD

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to Apex MD
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Semaglutide costs $299 a month, 62% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $399 a month, 60% above the $250 median for compounded tirzepatide across the sellers we compare
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

TrimRx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to TrimRx

Watch-outs

  • Semaglutide costs $299 a month, 62% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $399 a month, 60% above the $250 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Apex MD

Apex MD wins this one, 7.0 to 6.3, above all for an oral route if you will not self-inject. TrimRx fits better if compounded semaglutide at $299/month after a $199 first month is your priority.

Choose Apex MD if…

You want an oral route if you will not self-inject and an opening price near $299 a month.

Choose TrimRx if…

You want compounded semaglutide at $299/month after a $199 first month and an opening price near $299 a month.

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Semaglutide at $119/month, 37% below the typical price

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Oral orforglipron alongside the injectables

Apex MD vs TrimRx: FAQ

Neither on the entry price: Apex MD and TrimRx both start at about $299 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Apex MD lists 51 states; TrimRx does not publish where it ships. Confirm your state before paying.
Both include the clinician visit, the medication itself and shipping.
Apex MD has none. TrimRx has none.
No. Neither Apex MD nor TrimRx pays us anything.

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.