altRX vs Silhouette MD
altRX and Silhouette MD both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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If you are choosing between altRX and Silhouette MD, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. altRX leads our six-part score, 7.6 to 6.3. One of the two has an FDA warning letter on record, covered below.
altRX vs Silhouette MD price
altRX and Silhouette MD start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at altRX ($249 a month vs $299 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, altRX prices compounded injections and brand-name pens, while Silhouette MD prices compounded injections.
If you want the FDA-approved brand rather than a compounded version, altRX is the only one of the two with a brand-name price.
Where each one treats patients
altRX lists 50 states, and Silhouette MD does not publish where it ships.
Pricing
altRX
Silhouette MD
Lowest advertised tier ('as low as').
Lowest advertised tier ('as low as').
Oral formulation; lowest advertised tier.
Oral formulation; lowest advertised tier.
What each price covers
Both prices cover the clinician visit and the medication itself.
altRX's price also covers shipping, which Silhouette MD does not claim.
altRX is silent on lab work and coaching.
Silhouette MD is silent on shipping and lab work.
altRX
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Silhouette MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
Charged on top
Where each one scores higher
Overall, altRX scores 7.6 and Silhouette MD 6.3 out of 10.
altRX is stronger on user experience (8.0 vs 3.0), trust & safety (6.0 vs 4.0), accessibility (10.0 vs 5.0) and support (7.0 vs 5.5).
Silhouette MD is stronger on value (6.6 vs 5.0).
Effectiveness is within half a point.
altRX
7.6/10
Silhouette MD
6.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent altRX a warning letter dated June 8, 2026 (letter 728236), and it is still open.
Silhouette MD has no FDA warning letter on record with us.
Features & Coverage
| Feature | altRX | Silhouette MD |
|---|---|---|
| Starting Price | $149/mo | $149/mo |
| Features | ✓8 features | 5 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About altRX
Compounded plans open at $149 for semaglutide and $249 for tirzepatide. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer.
Read our full altRX review →About Silhouette MD
OpenLoop Health, the licensed clinical partner here, both writes the prescription and fulfills it. Every plan carries provider oversight plus full-service support, with no higher tier to buy. Two compounded GLP-1 molecules are stocked, semaglutide and tirzepatide, each available as a shot or taken by mouth. The positioning is concierge-style.
Read our full Silhouette MD review →Pros & Cons
altRX
What we like
- Tirzepatide costs $1249 a month, close to the $1249 median for brand-name tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- Names 4 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $1149 a month, 15% above the $997 median for brand-name semaglutide across the sellers we compare
- The FDA has issued altRX a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Silhouette MD
What we like
- Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
- The monthly price includes the medication and clinician visits
- We found no FDA warning letters issued to Silhouette MD
Watch-outs
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: coaching
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
altRX wins this one, 7.6 to 6.3, above all for semaglutide from $1149/month. Silhouette MD fits better if an oral route if you will not self-inject is your priority.
Choose altRX if…
You want semaglutide from $1149/month and an opening price near $149 a month.
Choose Silhouette MD if…
You want an oral route if you will not self-inject and an opening price near $149 a month.
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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.