Brand-Switch Dose-Equivalence Calculator

Medical disclaimer — read before using this tool

This tool does not provide medical advice. It is a patient-education aid, showing published trial data and FDA-label dose information word for word. Starting dose, timing, washout — every part of a brand switch is for a licensed prescriber to decide, with you. There is no FDA-approved dose-equivalence conversion between any of the four drugs listed here. Weight loss percentages are from independent phase 3 trials with different populations; they are not head-to-head equivalences. Compounded semaglutide and compounded tirzepatide are not FDA-approved; their dose ladders may differ from FDA-label doses.

Medical disclaimer

Patient education is the whole of what this tool is for. Nothing here is a treatment recommendation, a diagnosis, or medical advice. All brand-switch, dose, and timing decisions must be made with a licensed prescriber who can review your complete medical history, comorbidities, current medications, and insurance coverage. FDA-label dose ladders represent minimum titration intervals; your prescriber may individualize these based on tolerability. No FDA-approved conversion exists for dose equivalence between any two of the four drugs here. Cross-trial efficacy comparisons are not head-to-head data (except SURMOUNT-5 for Zepbound vs Wegovy). Compounded versions of semaglutide and tirzepatide are not FDA-approved products; consult your prescriber and compounding pharmacy for their specific dose ladders.