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SkyRx vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

SkyRx

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $199/month

Visit SkyRx
VS
CoreAge Rx logo

CoreAge Rx

9.1
★★★★4.6/5

Best for: semaglutide at $99/month, 48% under the register median

Visit CoreAge Rx

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, CoreAge Rx opens cheaper — $99/mo against $199, and CoreAge Rx finishes ahead, 9.1 to 6.7. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

SkyRx

All doses (flat)Compounded
$199/mo
semaglutide

199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

What’s included

SkyRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

CoreAge Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

SkyRx

6.7/10

Overall

CoreAge Rx

9.1/10

Value25%

4.6A
vs
B
9.7

Effectiveness25%

8.5A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
7.0

Features & Coverage

FeatureSkyRxCoreAge Rx
Starting Price$199/mo$99/mo
Features6 features6 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About SkyRx

Pay 12 months upfront and the rate is 199 dollars per month, one figure taking in shipping, the doctor visit, supplies and the drug, with insurance beside the point. Compounded semaglutide comes as oral drops or an injection; compounded tirzepatide is marked coming soon. 503B compounding pharmacies registered with the FDA do the dispensing. Coverage does not yet extend to all 50 states for GLP-1s. Draper, Utah is home to sky-rx.co, and support answers at 855-759-7979 or by email.

Read our full SkyRx review →

About CoreAge Rx

Shipping is free, 2-day, and reaches all 50 states. CoreAge Rx sells LegitScript-verified compounded semaglutide plus tirzepatide, with licensed physicians behind it and 24/7 support. Its own claim: nobody in the compounded GLP-1 space prices more competitively.

Read our full CoreAge Rx review →

Pros & Cons

SkyRx

What we like

  • Semaglutide at $199 a month, within the normal band around this register's $189 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

CoreAge Rx

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Tirzepatide at $149 a month, 44% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: CoreAge Rx

CoreAge Rx takes it, 9.1 against 6.7, and it is especially strong on semaglutide at $99/month, 48% under the register median. SkyRx is no weak second and may fit you better on compounded semaglutide at $199/month.

Choose SkyRx if…

You want compounded semaglutide at $199/month and an opening price near $199 a month.

Choose CoreAge Rx if…

You want semaglutide at $99/month, 48% under the register median and an opening price near $99 a month.

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6.5

Direct Meds

Compounded semaglutide at $249/month

7.7

Try Ageless

Semaglutide at $119/month, 37% under the register median

8.8

Found

Tirzepatide at $169/month, 37% under the register median

SkyRx vs CoreAge Rx: FAQ

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