Premium Health vs Tryozi
Premium Health costs $4 less a month, and both sell semaglutide and tirzepatide.
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Tryozi
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Tryozi →If you are choosing between Premium Health and Tryozi, the first difference is cost: Premium Health is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Tryozi leads our six-part score, 7.0 to 5.9. One of the two has an FDA warning letter on record, covered below.
Premium Health vs Tryozi price
Premium Health is the cheaper way in: $275 a month against $279 a month at Tryozi. That is $4 less each month (1% lower), or about $48 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Premium Health ($275 a month vs $279 a month); tirzepatide is cheaper at Tryozi ($379 a month vs $445 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Premium Health does not publish where it ships, and Tryozi lists 50 states.
Pricing
Premium Health
Tryozi
First 4 weeks $139 (50% off), then $279/mo. Multi-week plans are billed once and ship every 4 weeks: 12-week -22%, 24-week -29%, 52-week -47%.
First 4 weeks $189, then $379/mo, per the same first-month 50% structure.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
Premium Health is silent on lab work and coaching.
Tryozi is silent on lab work and coaching.
Premium Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Tryozi
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Tryozi scores 7.0 and Premium Health 5.9 out of 10.
Tryozi is stronger on user experience (8.0 vs 7.5), trust & safety (7.5 vs 3.5) and accessibility (10.0 vs 5.0).
Value, effectiveness and support are within half a point.
Premium Health
5.9/10
Tryozi
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Premium Health a warning letter dated February 20, 2026 (letter 721474), and it is still open.
Tryozi has no FDA warning letter on record with us.
Features & Coverage
| Feature | Premium Health | Tryozi |
|---|---|---|
| Starting Price | ✓$275/mo | $279/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About Premium Health
An all-inclusive membership prices compounded semaglutide at $275/month and compounded tirzepatide at $445/month, taking in drug, supplies, shipping, clinical support and visits with a provider. Going higher costs more: $100/month extra carries semaglutide to 2.4mg, $150/month extra carries tirzepatide to 15mg. Hallandale, Red Rock and Strive compound the medications with Vitamin B12 or B6. Premium Health holds LegitScript certification, runs its telehealth on Doxy.me under HIPAA, and gives the first consultation free.
Read our full Premium Health review →About Tryozi
Compounded GLP-1 injections at a flat price that holds as the dose rises. This Florida seller names all four of the 503A compounding pharmacies behind it.
Read our full Tryozi review →Pros & Cons
Premium Health
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- Semaglutide costs $275 a month, 49% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $445 a month, 78% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Premium Health a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Tryozi
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- We found no FDA warning letters issued to Tryozi
Watch-outs
- Semaglutide costs $279 a month, 51% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $379 a month, 52% above the $250 median for compounded tirzepatide across the sellers we compare
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Tryozi wins this one, 7.0 to 5.9, above all for coverage in all 50 states, which most sellers will not confirm. Premium Health undercuts it by $4 a month, so if the monthly bill is what decides it, Premium Health is the pick. Premium Health fits better if compounded semaglutide at $275/month is your priority.
Choose Premium Health if…
You want compounded semaglutide at $275/month and an opening price near $275 a month.
Choose Tryozi if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $279 a month.
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