GLP Watchdog

PlushCare vs TrimRx

Neither PlushCare nor TrimRx has an FDA warning letter on record. On compounded semaglutide injection, PlushCare costs $1,800 less a year at standing rates: $149 a month against $299 a month at TrimRx.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

PlushCare / TrimRx

PlushCare logo

PlushCare

6.4/10

Featured pick (affiliate partner)

TrimRx logo

TrimRx

6.4/10

FDA warning letters
None on record
None on record
Pharmacy
None named in our record
None named in our record
Lowest standing price
$149/moCompounded semaglutide injection
$299/moCompounded semaglutide injection
States
All 50 states
No state list published
Checked
Prices captured Record checked September 2026
Prices captured Record checked October 2026
Visit PlushCare
Visit TrimRx

TrimRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. PlushCare pays us nothing. The scores are computed the same way for both and are shown as computed (PlushCare 6.4, TrimRx 6.4). How we are paid

What the record shows

  1. 01

    Neither PlushCare nor TrimRx has an FDA warning letter on record.

  2. 02

    Neither names the pharmacy that compounds its medication.

  3. 03

    On compounded semaglutide injection, PlushCare costs $1,800 less a year at standing rates: $149 a month against $299 a month at TrimRx.

  4. 04

    Only TrimRx lists a price for brand-name semaglutide pen and brand-name tirzepatide pen.

  5. 05

    PlushCare lists all 50 states. TrimRx publishes no state list.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

PlushCare

TrimRx

Compounded semaglutide injection

$149/moLower

$1,788 a year

$299/mo

$3,588 a year

Compounded tirzepatide injection

$399/mo

$4,788 a year

$399/mo

$4,788 a year

Brand-name semaglutide pen
Not sold or not priced

$1,299/mo

$15,588 a year

Brand-name tirzepatide pen
Not sold or not priced

$1,399/mo

$16,788 a year

Price includes
Not stated
Medication, clinician visits, shipping
Billed separately
Medication, clinician visits, labs
Not stated
Cancel any time
Yes, stated
Yes, stated
Minimum term
None; membership is billed monthly or annually
None on the monthly plan; multi-month plans are prepaid
Refunds
Appointment cost only; membership fees and prescriptions are not refunded
Full refund if a provider finds you ineligible; other refund requests within 28 days of payment

Read off each seller’s own pages. PlushCare: July 10, 2026. TrimRx: October 25, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for PlushCare

6.4/10
  • $1,800 a year less on compounded semaglutide injection
  • Names no compounding pharmacy
  • Price leaves out medication, clinician visits and labs
Visit PlushCare

The case for TrimRx

6.4/10
Featured pick (affiliate partner)
  • Sells brand-name semaglutide pen and brand-name tirzepatide pen, which PlushCare does not price
  • Price includes clinician visits
  • Names no compounding pharmacy
  • Publishes no state list
Visit TrimRx

Scores

PlushCare 6.4 · TrimRx 6.4 out of 10. Six weighted parts.

Value25%

3.0A
vs
B
2.2

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
6.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

0.0A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

PlushCare vs TrimRx: questions

Neither PlushCare nor TrimRx has an FDA warning letter on record. Letters are matched to a seller by company, domain and address, never by a similar name.
Neither names the pharmacy that compounds its medication.
PlushCare, by $1,800 a year at standing rates. PlushCare: $149 a month, about $1,788 a year. TrimRx: $299 a month, about $3,588 a year.
PlushCare states you can cancel at any time; refunds: appointment cost only; membership fees and prescriptions are not refunded. TrimRx states you can cancel at any time; refunds: full refund if a provider finds you ineligible; other refund requests within 28 days of payment.
TrimRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. PlushCare pays us nothing. The scores are computed the same way for both and are shown as computed (PlushCare 6.4, TrimRx 6.4).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register

Brand names on this page are registered marks. Novo Nordisk holds Wegovy®, Ozempic® and Rybelsus®; Eli Lilly holds Zepbound®, Mounjaro® and Foundayo®. Neither company has any tie to GLP Watchdog. Trademarks