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Next Vial vs Wisp

Wisp costs $24.97 less a month, and both sell semaglutide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Next Vial logo

Next Vial

5.7
★★★☆☆2.9/5

Best for: compounded semaglutide at $249.97/month

Visit Next Vial →
VS
Wisp logo

Wisp

7.0
★★★★☆3.5/5

Best for: an oral route if you will not self-inject

Visit Wisp →

If you are choosing between Next Vial and Wisp, the first difference is cost: Wisp is $24.97 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. Wisp leads our six-part score, 7.0 to 5.7.

Next Vial vs Wisp price

Wisp is the cheaper way in: $225 a month against $249.97 a month at Next Vial. That is $24.97 less each month (10% lower), or about $299.64 over a year of treatment.

Drug by drug: Semaglutide is cheaper at Wisp ($225 a month vs $249.97 a month).

Medications and formats

Both sell semaglutide.

On format they match: each offers compounded injections.

Where each one treats patients

Next Vial lists 49 states, and Wisp lists 39 states.

They overlap in 38 states. Next Vial alone covers 11 states, including Alabama, Arkansas, Florida and Louisiana. Wisp alone covers Alaska.

Pricing

Next Vial

StandardCompounded
$249.97/mo
semaglutide

Starting monthly rate for GLP-1 program; tirzepatide rate not published.

Wisp

Compounded sublingual semaglutide drops 15mLCompounded
$225/mo
semaglutide
Metabolic Support & GLP-1 Boost capsules (adjunct supplement, not a prescription GLP-1)supplement subscription
$54/mo

Monthly subscription supplement, NOT a prescription GLP-1 medication. 'subscription' in form keeps it out of the GLP-1 hero price. drug omitted intentionally.

Weight Care consult fee (Zepbound medication billed separately by your pharmacy)Brand-name
$99/mo
tirzepatide

Wisp's $99 covers the consult and prescription for brand Zepbound; the medication is picked up and paid for at your local pharmacy.

What each price covers

Both prices cover the medication itself and shipping.

Next Vial's price also covers the clinician visit, which Wisp does not claim.

Next Vial is silent on lab work and coaching.

Wisp is silent on the clinician visit, lab work and coaching.

Next Vial

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Wisp

Covered by the monthly price

Medication

In the price

Clinician visits

Not stated

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Wisp scores 7.0 and Next Vial 5.7 out of 10.

Next Vial is stronger on accessibility (9.8 vs 8.2) and support (7.0 vs 4.5).

Wisp is stronger on value (3.6 vs 2.8), effectiveness (10.0 vs 8.5), user experience (8.0 vs 3.0) and trust & safety (7.5 vs 5.0).

How we score

Next Vial

5.7/10

Overall

Wisp

7.0/10

Value25%

2.8A
vs
B
3.6

Effectiveness25%

8.5A
vs
B
10.0

User Experience15%

3.0A
vs
B
8.0

Trust & Safety15%

5.0A
vs
B
7.5

Accessibility10%

9.8A
vs
B
8.2

Support10%

7.0A
vs
B
4.5

FDA warning letters

Neither Next Vial nor Wisp has an FDA warning letter on record with us.

Features & Coverage

FeatureNext VialWisp
Starting Price$249.97/mo✓$225/mo
Features7 features✓8 features
States Available✓4939
Compounded✓ Yes✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Next Vial

An online marketplace that connects patients to licensed providers for compounded semaglutide and tirzepatide injections, microdose options included. It is LegitScript verified and names its dispensing pharmacy: Manifest Pharmacy in Greer, SC. There is no membership required, and one price covers the consultation, the medication and free shipping. It serves 49 states.

Read our full Next Vial review →

About Wisp

$225/month buys a compounded sublingual semaglutide drops formulation from Wisp. Its weight care vertical also stocks three brand names: Saxenda, Zepbound, and Wegovy. A board-certified provider completes the review inside 24-72 hours. LegitScript certification is in place.

Read our full Wisp review →

Pros & Cons

Next Vial

What we like

  • The monthly price includes the medication, clinician visits and shipping
  • Serves 49 states
  • We found no FDA warning letters issued to Next Vial

Watch-outs

  • Semaglutide costs $249.97 a month, 35% above the $185 median for compounded semaglutide across the sellers we compare
  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Wisp

What we like

  • Tirzepatide costs $99 a month, 92% below the $1249 median for brand-name tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication and shipping
  • We found no FDA warning letters issued to Wisp

Watch-outs

  • Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
  • Serves only 39 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Wisp

Wisp wins this one, 7.0 to 5.7, above all for an oral route if you will not self-inject. It also costs $24.97 less each month than Next Vial. Next Vial fits better if compounded semaglutide at $249.97/month is your priority.

Choose Next Vial if…

You want compounded semaglutide at $249.97/month and an opening price near $249.97 a month.

Choose Wisp if…

You want an oral route if you will not self-inject and an opening price near $225 a month.

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9.4

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Knowing which pharmacy fills the vial: it names VialsRx

6.4

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Oral orforglipron alongside the injectables

9.0

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Starting below a standard dose, with microdose tiers

Next Vial vs Wisp: FAQ

Wisp. It starts at $225 a month; Next Vial starts at $249.97 a month, $24.97 more per month.
Yes, both sell semaglutide.
Next Vial: 49 states against 39, with 38 in common.
Both include the medication itself and shipping. Only Next Vial includes the clinician visit.
Next Vial has none. Wisp has none.
No. Neither Next Vial nor Wisp pays us anything.

Or see the full category ranking.