MEDVi vs Next Vial
MEDVi and Next Vial both sell semaglutide; this is how their prices, coverage and records differ.
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If you are choosing between MEDVi and Next Vial, price alone will not settle it. Both prescribe semaglutide, so moving from one to the other would not change your drug. MEDVi leads our six-part score, 7.1 to 5.7. One of the two has an FDA warning letter on record, covered below.
MEDVi vs Next Vial price
MEDVi and Next Vial start at within a dollar of each other ($249 and $249.97 a month), so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $249 a month.
Medications and formats
Both sell semaglutide.
On format they match: each offers compounded injections.
Where each one treats patients
MEDVi lists 48 states, and Next Vial lists 49 states.
They overlap in 47 states. MEDVi alone covers Alaska. Next Vial alone covers Mississippi and North Dakota.
Pricing
MEDVi
Refills are locked in at $299. The first month is $179 in the 'SUMMER Sale,' and some MEDVi landing pages offer the first month at $149.
Flat 'Starting at $249' — no intro discount shown.
$99 Membership + Medication Cost — medication cost not published (varies/insurance may reimburse). 'Availability is subject to change.'
$99 Membership + Medication Cost — medication cost not published. COMPOUNDED tirzepatide ($349 in our current entry) is no longer published anywhere on glp1.medvi.org, home.medvi.org, or the intake flow (0 mentions) — treat as discontinued/not published, do not carry the $349 row forward.
Next Vial
Starting monthly rate for GLP-1 program; tirzepatide rate not published.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
MEDVi's price also covers coaching, which Next Vial does not claim.
MEDVi is silent on lab work.
Next Vial is silent on lab work and coaching.
MEDVi
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Next Vial
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, MEDVi scores 7.1 and Next Vial 5.7 out of 10.
MEDVi is stronger on effectiveness (10.0 vs 8.5), user experience (8.0 vs 3.0), trust & safety (6.0 vs 5.0) and support (8.5 vs 7.0).
Value and accessibility are within half a point.
MEDVi
7.1/10
Next Vial
5.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent MEDVi a warning letter dated February 20, 2026 (letter 721455), and it is still open.
Next Vial has no FDA warning letter on record with us.
Features & Coverage
| Feature | MEDVi | Next Vial |
|---|---|---|
| Starting Price | ✓$249/mo | $249.97/mo |
| Features | 7 features | 7 features |
| States Available | 48 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About MEDVi
Two clinical groups do the treating at MEDVi: CareGLP Affiliated P.C.s, plus clinicians from OpenLoop Health. Its weight-loss menu holds compounded GLP-1s, injections and tablets alike, the molecule being semaglutide, next to Zepbound and Wegovy under their brand names. Licensed US pharmacies fill all of it.
Read our full MEDVi review →About Next Vial
An online marketplace that connects patients to licensed providers for compounded semaglutide and tirzepatide injections, microdose options included. It is LegitScript verified and names its dispensing pharmacy: Manifest Pharmacy in Greer, SC. There is no membership required, and one price covers the consultation, the medication and free shipping. It serves 49 states.
Read our full Next Vial review →Pros & Cons
MEDVi
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits, shipping and coaching
- Serves 48 states
- Names 3 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- The FDA has issued MEDVi a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Next Vial
What we like
- The monthly price includes the medication, clinician visits and shipping
- Serves 49 states
- We found no FDA warning letters issued to Next Vial
Watch-outs
- Semaglutide costs $249.97 a month, 36% above the $184 median for compounded semaglutide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
MEDVi wins this one, 7.1 to 5.7, above all for knowing which pharmacy fills the vial: it names Triad Rx. Next Vial fits better if compounded semaglutide at $249.97/month is your priority.
Choose MEDVi if…
You want knowing which pharmacy fills the vial: it names Triad Rx and an opening price near $249 a month.
Choose Next Vial if…
You want compounded semaglutide at $249.97/month and an opening price near $249.97 a month.
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Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →MEDVi vs Next Vial: FAQ
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- Next Vial vs Tell Her Doc
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Or see the full category ranking.