MangoRx vs He & She MD
An in-depth comparison of two leading GLP-1 Providers
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He & She MD
Best for: starting below a standard dose, with microdose tiers
Visit He & She MD →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $299, and He & She MD finishes ahead, 9.3 to 4.6. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
MangoRx
Slim = oral semaglutide + Vitamin B6, 30-day supply of daily mint-flavored ODTs. Subscribe & Save: 10% off initial and all auto-refill orders + free UPS Ground shipping; auto-refills every 25 days. Provider visit and shipping advertised as free on all orders. No injectable option, no tirzepatide product page. Insurance not accepted.
He & She MD
⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.
Injectable tirzepatide intro $199/mo (regular $289/mo)
What’s included
MangoRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
He & She MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MangoRx
4.6/10
He & She MD
9.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MangoRx | He & She MD |
|---|---|---|
| Starting Price | $299/mo | ✓$99/mo |
| Features | 3 features | ✓8 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MangoRx
Verification is still outstanding on the GLP-1 side of MangoRx (Mangoceuticals). Pricing, states, pharmacy partners, and clinical workflow have not cleared our YMYL check, so this stays a stub entry. The men's health platform sells compounded GLP-1 weight management, and beside it hair loss programs, ED treatment, and testosterone replacement therapy.
Read our full MangoRx review →About He & She MD
GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.
Read our full He & She MD review →Pros & Cons
MangoRx
What we like
- The monthly figure covers medication and consult
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Semaglutide at $299 a month, 50% above the $199 register median for the same drug and form
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
He & She MD
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
He & She MD takes it, 9.3 against 4.6, and it is especially strong on starting below a standard dose, with microdose tiers. MangoRx is no weak second and may fit you better on an oral route if you will not self-inject.
Choose MangoRx if…
You want an oral route if you will not self-inject and an opening price near $299 a month.
Choose He & She MD if…
You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.
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Found
Tirzepatide at $169/month, 37% under the register median
From $99/mo
Get started →Telos Rx
Starting below a standard dose, with microdose tiers
From $49/mo
Get started →MyDrHank
An oral route if you will not self-inject
From $25/mo
Get started →MangoRx vs He & She MD: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.