Lyfe Rx vs MDExam
Lyfe Rx and MDExam both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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MDExam
Best for: coaching bundled into the price rather than sold separately
Visit MDExam →If you are choosing between Lyfe Rx and MDExam, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Lyfe Rx leads our six-part score, 6.4 to 6.0. One of the two has an FDA warning letter on record, covered below.
Lyfe Rx vs MDExam price
Lyfe Rx and MDExam start at the same figure, $225 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $225 a month; tirzepatide is cheaper at MDExam ($258 a month vs $299 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Neither Lyfe Rx nor MDExam publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
Lyfe Rx
MDExam
What each price covers
Both prices cover the clinician visit and the medication itself.
Lyfe Rx's price also covers shipping, which MDExam does not claim.
MDExam's price also covers coaching, which Lyfe Rx does not claim.
Lyfe Rx is silent on lab work and coaching.
MDExam is silent on shipping and lab work.
Lyfe Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
MDExam
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
In the price
Where each one scores higher
Overall, Lyfe Rx scores 6.4 and MDExam 6.0 out of 10.
Lyfe Rx is stronger on user experience (8.0 vs 3.0).
MDExam is stronger on value (4.8 vs 3.7) and trust & safety (4.0 vs 3.5).
Effectiveness, accessibility and support are within half a point.
Lyfe Rx
6.4/10
MDExam
6.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Lyfe Rx has an FDA warning letter on record.
MDExam has no FDA warning letter on record with us.
Features & Coverage
| Feature | Lyfe Rx | MDExam |
|---|---|---|
| Starting Price | $225/mo | $225/mo |
| Features | ✓3 features | 2 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About Lyfe Rx
Lyfe Rx sells compounded semaglutide at $289 and compounded tirzepatide at $399, shipping to all 50 states. The FDA issued it a warning letter on 09/09/2025 for misbranding compounded GLP-1 products.
Read our full Lyfe Rx review →About MDExam
MDExam is a telehealth seller offering GLP-1 medications alongside other prescription services.
Read our full MDExam review →Pros & Cons
Lyfe Rx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Lyfe Rx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
MDExam
What we like
- Tirzepatide costs $258 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and coaching
- We found no FDA warning letters issued to MDExam
Watch-outs
- Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Lyfe Rx wins this one, 6.4 to 6.0, above all for compounded semaglutide at $225/month. MDExam fits better if coaching bundled into the price rather than sold separately is your priority.
Choose Lyfe Rx if…
You want compounded semaglutide at $225/month and an opening price near $225 a month.
Choose MDExam if…
You want coaching bundled into the price rather than sold separately and an opening price near $225 a month.
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