EllieMD vs Lyfe Rx
Lyfe Rx costs $4 less a month, and both sell semaglutide and tirzepatide.
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If you are choosing between EllieMD and Lyfe Rx, the first difference is cost: Lyfe Rx is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Lyfe Rx leads our six-part score, 6.4 to 5.8. One of the two has an FDA warning letter on record, covered below.
EllieMD vs Lyfe Rx price
Lyfe Rx is the cheaper way in: $225 a month against $229 a month at EllieMD. That is $4 less each month (2% lower), or about $48 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Lyfe Rx ($225 a month vs $229 a month); tirzepatide is cheaper at EllieMD ($239 a month vs $299 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Neither EllieMD nor Lyfe Rx publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
EllieMD
Lyfe Rx
What each price covers
Both prices cover the clinician visit and shipping.
Lyfe Rx's price also covers the medication itself, which EllieMD does not claim.
EllieMD is silent on the medication itself and coaching.
Lyfe Rx is silent on lab work and coaching.
That matters most for the drug: unless EllieMD confirms otherwise, budget for medication on top of its listed price.
EllieMD
Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Charged on top
Coaching
Not stated
Lyfe Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Lyfe Rx scores 6.4 and EllieMD 5.8 out of 10.
EllieMD is stronger on value (5.3 vs 3.7) and trust & safety (4.0 vs 3.5).
Lyfe Rx is stronger on user experience (8.0 vs 3.0) and support (7.0 vs 4.0).
Effectiveness and accessibility are within half a point.
EllieMD
5.8/10
Lyfe Rx
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Lyfe Rx has an FDA warning letter on record.
EllieMD has no FDA warning letter on record with us.
Features & Coverage
| Feature | EllieMD | Lyfe Rx |
|---|---|---|
| Starting Price | $229/mo | ✓$225/mo |
| Features | 2 features | ✓3 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About EllieMD
EllieMD is a women-focused telehealth weight loss clinic that prescribes GLP-1 medications.
Read our full EllieMD review →About Lyfe Rx
Lyfe Rx sells compounded semaglutide at $289 and compounded tirzepatide at $399, shipping to all 50 states. The FDA issued it a warning letter on 09/09/2025 for misbranding compounded GLP-1 products.
Read our full Lyfe Rx review →Pros & Cons
EllieMD
What we like
- Tirzepatide costs $239 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes clinician visits and shipping
- We found no FDA warning letters issued to EllieMD
Watch-outs
- Semaglutide costs $229 a month, 24% above the $185 median for compounded semaglutide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: lab work
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Lyfe Rx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Lyfe Rx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Lyfe Rx wins this one, 6.4 to 5.8, above all for compounded semaglutide at $225/month. It also costs $4 less each month than EllieMD.
Choose EllieMD if…
You want broader feature coverage and an opening price near $229 a month.
Choose Lyfe Rx if…
You want compounded semaglutide at $225/month and an opening price near $225 a month.
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Knowing which pharmacy fills the vial: it names Tru Meds Rx
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Get started →EllieMD vs Lyfe Rx: FAQ
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