FMmeds vs Lyfe Rx
FMmeds and Lyfe Rx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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FMmeds
Best for: coverage in all 50 states, which most sellers will not confirm
Visit FMmeds →
If you are choosing between FMmeds and Lyfe Rx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. FMmeds leads our six-part score, 7.2 to 6.4. One of the two has an FDA warning letter on record, covered below.
FMmeds vs Lyfe Rx price
FMmeds and Lyfe Rx start at the same figure, $225 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $225 a month; tirzepatide is cheaper at FMmeds ($265 a month vs $299 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
FMmeds lists 51 states, and Lyfe Rx does not publish where it ships.
Pricing
FMmeds
Standing month-to-month rate. Prepay cadences work out to $129/mo (3-month), $119/mo (6-month) and $95/mo (12-month) — the homepage currently headlines the $95 figure, which is the 12-month prepay equivalent.
Standing month-to-month rate. Prepay cadences work out to $195/mo (3-month), $175/mo (6-month) and $145/mo (12-month) — the homepage headlines $145.
Lyfe Rx
What each price covers
Both prices cover shipping.
Lyfe Rx's price also covers the clinician visit and the medication itself, which FMmeds does not claim.
FMmeds is silent on the clinician visit, the medication itself, lab work and coaching.
Lyfe Rx is silent on lab work and coaching.
That matters most for the drug: unless FMmeds confirms otherwise, budget for medication on top of its listed price.
FMmeds
Covered by the monthly price
Medication
Not stated
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Lyfe Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, FMmeds scores 7.2 and Lyfe Rx 6.4 out of 10.
FMmeds is stronger on value (4.6 vs 3.7), trust & safety (5.5 vs 3.5) and accessibility (10.0 vs 5.0).
Lyfe Rx is stronger on support (7.0 vs 5.0).
Effectiveness and user experience are within half a point.
FMmeds
7.2/10
Lyfe Rx
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Lyfe Rx has an FDA warning letter on record.
FMmeds has no FDA warning letter on record with us.
Features & Coverage
| Feature | FMmeds | Lyfe Rx |
|---|---|---|
| Starting Price | $225/mo | $225/mo |
| Features | ✓8 features | 3 features |
| States Available | 51 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About FMmeds
Vitamin B12 is co-formulated into both the compounded semaglutide and the compounded tirzepatide sold here. No membership charge applies, and the first visit is free unless the patient is approved. Dose strength does not move the price. Commit to 12 months and semaglutide falls to $95/mo, tirzepatide to $145/mo. FMmeds works out of Manhattan Beach, names Manifest Pharmacy of Greer, SC as its 503A partner, and covers all 50 states and DC.
Read our full FMmeds review →About Lyfe Rx
Lyfe Rx sells compounded semaglutide at $289 and compounded tirzepatide at $399, shipping to all 50 states. The FDA issued it a warning letter on 09/09/2025 for misbranding compounded GLP-1 products.
Read our full Lyfe Rx review →Pros & Cons
FMmeds
What we like
- Tirzepatide costs $265 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes shipping
- Serves all 50 states
- We found no FDA warning letters issued to FMmeds
Watch-outs
- Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Lyfe Rx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $225 a month, 22% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Lyfe Rx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
FMmeds wins this one, 7.2 to 6.4, above all for coverage in all 50 states, which most sellers will not confirm. Lyfe Rx fits better if compounded semaglutide at $225/month is your priority.
Choose FMmeds if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $225 a month.
Choose Lyfe Rx if…
You want compounded semaglutide at $225/month and an opening price near $225 a month.
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