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LunaRx vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
LunaRx logo

LunaRx

6.3
★★★☆☆3.2/5

Best for: seeing what it charges before you answer any medical questions

Visit LunaRx
VS
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $199, and He & She MD finishes ahead, 9.3 to 6.3. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

LunaRx

Starting — Lean Muscle Foundation stackCompounded
$199/mo
semaglutide

Published headline is "from $199/mo" for the entry Foundation stack (compounded semaglutide + muscle-protective peptides). Specific tier and tirzepatide pricing are confirmed only after a provider review; no per-dose price list is published.

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

What’s included

LunaRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

LunaRx

6.3/10

Overall

He & She MD

9.3/10

Value25%

3.0A
vs
B
9.7

Effectiveness25%

8.5A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
8.5

Features & Coverage

FeatureLunaRxHe & She MD
Starting Price$199/mo$99/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About LunaRx

$199/month is where programs open, though which tier you land in, and what tirzepatide costs, only becomes clear after a physician reviews you. LunaRx LLC works in Spanish and English both, around an idea it calls metabolic recomposition: not an open-ended prescription but compounded GLP-1 therapy joined to peptides that protect muscle and a taper structured as an off-ramp. CareNexus Clinic PC, an independent medical group, directs care under physicians, and a patient who is not approved pays $0. Compounded medications are not FDA-approved.

Read our full LunaRx review →

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

Pros & Cons

LunaRx

What we like

  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 6.3, and it is especially strong on starting below a standard dose, with microdose tiers. LunaRx is no weak second and may fit you better on seeing what it charges before you answer any medical questions.

Choose LunaRx if…

You want seeing what it charges before you answer any medical questions and an opening price near $199 a month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

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6.5

Direct Meds

Compounded semaglutide at $249/month

7.7

Try Ageless

Semaglutide at $119/month, 37% under the register median

8.8

Found

Tirzepatide at $169/month, 37% under the register median

LunaRx vs He & She MD: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.