LillyDirect Foundayo vs He & She MD
An in-depth comparison of two leading GLP-1 Providers
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LillyDirect Foundayo
Best for: oral orforglipron alongside the injectables
Visit LillyDirect Foundayo →
He & She MD
Best for: starting below a standard dose, with microdose tiers
Visit He & She MD →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $149, and He & She MD finishes ahead, 9.3 to 7.2. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
LillyDirect Foundayo
Requires commercial insurance; Medicare/Medicaid not eligible. 'Starting at $25 per month'.
Regular self-pay price, 1-month (30-day) supply.
Regular self-pay price, 1-month supply.
Regular self-pay price, 1-month supply.
Regular self-pay price $349; available for $299 via an automatic purchase offer ONLY if you complete your refill within 45 days of the delivery/receipt date of your previous Foundayo fill (14.5/17.2 mg only).
He & She MD
⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.
Injectable tirzepatide intro $199/mo (regular $289/mo)
What’s included
LillyDirect Foundayo
Inclusions not disclosed.
He & She MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
LillyDirect Foundayo
7.2/10
He & She MD
9.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | LillyDirect Foundayo | He & She MD |
|---|---|---|
| Starting Price | $149/mo | ✓$99/mo |
| Features | 5 features | ✓8 features |
| States Available | ✓51 | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About LillyDirect Foundayo
Any licensed prescriber can write it, but LillyDirect will not ship without a valid US prescription. Eli Lilly runs this channel itself, direct-pay, and what it sells is Foundayo (orforglipron): for weight loss, the first oral GLP-1 pill. Commercially insured patients holding the Lilly Savings Card pay $25/month. Paying cash costs $149-$299/month, depending on labeled dose.
Read our full LillyDirect Foundayo review →About He & She MD
GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.
Read our full He & She MD review →Pros & Cons
LillyDirect Foundayo
What we like
- Orforglipron at $149 a month, within the normal band around this register's $149 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
He & She MD
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
He & She MD takes it, 9.3 against 7.2, and it is especially strong on starting below a standard dose, with microdose tiers. LillyDirect Foundayo is no weak second and may fit you better on oral orforglipron alongside the injectables.
Choose LillyDirect Foundayo if…
You want oral orforglipron alongside the injectables and an opening price near $149 a month.
Choose He & She MD if…
You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.
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Direct Meds
Compounded semaglutide at $249/month
From $249/mo
Get started →Try Ageless
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Found
Tirzepatide at $169/month, 37% under the register median
From $99/mo
Get started →LillyDirect Foundayo vs He & She MD: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.