Lean Rx vs Premium Health
Lean Rx costs $9 less a month, and both sell semaglutide and tirzepatide.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Lean Rx
Best for: seeing what it charges before you answer any medical questions
Visit Lean Rx →
If you are choosing between Lean Rx and Premium Health, the first difference is cost: Lean Rx is $9 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Lean Rx leads our six-part score, 6.4 to 5.9. One of the two has an FDA warning letter on record, covered below.
Lean Rx vs Premium Health price
Lean Rx is the cheaper way in: $266 a month against $275 a month at Premium Health. That is $9 less each month (3% lower), or about $108 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Lean Rx ($266 a month vs $275 a month); tirzepatide is cheaper at Lean Rx ($399 a month vs $445 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Neither Lean Rx nor Premium Health publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
Lean Rx
Premium Health
What each price covers
Both prices cover the medication itself.
Premium Health's price also covers the clinician visit and shipping, which Lean Rx does not claim.
Lean Rx is silent on the clinician visit, shipping, lab work and coaching.
Premium Health is silent on lab work and coaching.
Lean Rx
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
Premium Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Lean Rx scores 6.4 and Premium Health 5.9 out of 10.
Lean Rx is stronger on value (3.0 vs 2.1) and trust & safety (6.5 vs 3.5).
Premium Health is stronger on support (7.0 vs 5.0).
Effectiveness, user experience and accessibility are within half a point.
Lean Rx
6.4/10
Premium Health
5.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Premium Health a warning letter dated February 20, 2026 (letter 721474), and it is still open.
Lean Rx has no FDA warning letter on record with us.
Features & Coverage
| Feature | Lean Rx | Premium Health |
|---|---|---|
| Starting Price | ✓$266/mo | $275/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About Lean Rx
Injectable, sublingual and tablet forms are all offered, at $266 per month upward for the compounded GLP-1 semaglutide and $399 per month upward for compounded tirzepatide. An online medical history comes first. Next an independent licensed provider takes a telehealth call and writes where appropriate, and the parcel goes home. Lean Rx works out of Sacramento, advertises pricing with nothing hidden, and states that it is a technology company rather than a healthcare provider. No list of states exists.
Read our full Lean Rx review →About Premium Health
An all-inclusive membership prices compounded semaglutide at $275/month and compounded tirzepatide at $445/month, taking in drug, supplies, shipping, clinical support and visits with a provider. Going higher costs more: $100/month extra carries semaglutide to 2.4mg, $150/month extra carries tirzepatide to 15mg. Hallandale, Red Rock and Strive compound the medications with Vitamin B12 or B6. Premium Health holds LegitScript certification, runs its telehealth on Doxy.me under HIPAA, and gives the first consultation free.
Read our full Premium Health review →Pros & Cons
Lean Rx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication
- We found no FDA warning letters issued to Lean Rx
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Premium Health
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- Semaglutide costs $275 a month, 49% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $445 a month, 78% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Premium Health a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Lean Rx wins this one, 6.4 to 5.9, above all for seeing what it charges before you answer any medical questions. It also costs $9 less each month than Premium Health. Premium Health fits better if compounded semaglutide at $275/month is your priority.
Choose Lean Rx if…
You want seeing what it charges before you answer any medical questions and an opening price near $266 a month.
Choose Premium Health if…
You want compounded semaglutide at $275/month and an opening price near $275 a month.
Ready to start? GLP-1 providers we have vetted
Telehealth providers, vetted by us, prescribing GLP-1 online.
Vetted by our editors · no insurance required
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Trimi Health
Knowing which pharmacy fills the vial: it names VialsRx
From $99/mo
Get started →ShedRx
Oral orforglipron alongside the injectables
From $149/mo
Get started →bmiMD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Lean Rx vs Premium Health: FAQ
Close alternatives to Lean Rx and Premium Health
- Lean Rx vs ElleS
- Lean Rx vs RedBox Rx
- Lean Rx vs Aspen
- Premium Health vs Aspen
- Premium Health vs Joey Med
- Premium Health vs Society of You
Or see the full category ranking.