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He & She MD vs Medi-Weightloss

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD
VS
Medi-Weightloss logo

Medi-Weightloss

5.5
★★☆☆2.8/5

Best for: semaglutide from $199/month

Visit Medi-Weightloss

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $199, and He & She MD finishes ahead, 9.3 to 5.5. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

Medi-Weightloss

New patient visitBrand-name
$199/mo
semaglutide

What’s included

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Medi-Weightloss

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

He & She MD

9.3/10

Overall

Medi-Weightloss

5.5/10

Value25%

9.7A
vs
B
5.0

Effectiveness25%

10.0A
vs
B
9.0

User Experience15%

8.0A
vs
B
2.5

Trust & Safety15%

8.5A
vs
B
4.0

Accessibility10%

10.0A
vs
B
5.0

Support10%

8.5A
vs
B
5.0

Features & Coverage

FeatureHe & She MDMedi-Weightloss
Starting Price$99/mo$199/mo
Features8 features8 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

About Medi-Weightloss

A new-patient visit at Medi-Weightloss runs about $199 and covers a medical assessment, labs and a GLP-1 eligibility review; what medication costs after that depends on the plan. The physician-supervised brand has 130-plus locations nationwide alongside telehealth, and prescribes branded Wegovy and Zepbound, compounded semaglutide and compounded tirzepatide, plus older agents such as phentermine. Programs are evidence-based and include body-composition analysis and personalized plans. Insurance is accepted at many locations, and HSA/FSA funds are welcome.

Read our full Medi-Weightloss review →

Pros & Cons

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Medi-Weightloss

What we like

  • Semaglutide at $199 a month, 85% below the $1299 median for the same drug and form across this register
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • No FDA warning letter matched this operator when we searched our enforcement register
  • Baseline bloodwork is required before a prescription

Watch-outs

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 5.5, and it is especially strong on starting below a standard dose, with microdose tiers. Medi-Weightloss is no weak second and may fit you better on semaglutide from $199/month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

Choose Medi-Weightloss if…

You want semaglutide from $199/month and an opening price near $199 a month.

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8.5

Strut Health

Semaglutide at $99/month, 48% under the register median

7.9

Oak

Semaglutide at $119/month, 37% under the register median

6.5

Direct Meds

Compounded semaglutide at $249/month

He & She MD vs Medi-Weightloss: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.