He & She MD vs Medi-Weightloss
An in-depth comparison of two leading GLP-1 Providers
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He & She MD
Best for: starting below a standard dose, with microdose tiers
Visit He & She MD →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $199, and He & She MD finishes ahead, 9.3 to 5.5. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
He & She MD
⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.
Injectable tirzepatide intro $199/mo (regular $289/mo)
Medi-Weightloss
What’s included
He & She MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Medi-Weightloss
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
He & She MD
9.3/10
Medi-Weightloss
5.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | He & She MD | Medi-Weightloss |
|---|---|---|
| Starting Price | ✓$99/mo | $199/mo |
| Features | 8 features | 8 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About He & She MD
GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.
Read our full He & She MD review →About Medi-Weightloss
A new-patient visit at Medi-Weightloss runs about $199 and covers a medical assessment, labs and a GLP-1 eligibility review; what medication costs after that depends on the plan. The physician-supervised brand has 130-plus locations nationwide alongside telehealth, and prescribes branded Wegovy and Zepbound, compounded semaglutide and compounded tirzepatide, plus older agents such as phentermine. Programs are evidence-based and include body-composition analysis and personalized plans. Insurance is accepted at many locations, and HSA/FSA funds are welcome.
Read our full Medi-Weightloss review →Pros & Cons
He & She MD
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Medi-Weightloss
What we like
- Semaglutide at $199 a month, 85% below the $1299 median for the same drug and form across this register
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- No FDA warning letter matched this operator when we searched our enforcement register
- Baseline bloodwork is required before a prescription
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Our Verdict
He & She MD takes it, 9.3 against 5.5, and it is especially strong on starting below a standard dose, with microdose tiers. Medi-Weightloss is no weak second and may fit you better on semaglutide from $199/month.
Choose He & She MD if…
You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.
Choose Medi-Weightloss if…
You want semaglutide from $199/month and an opening price near $199 a month.
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Strut Health
Semaglutide at $99/month, 48% under the register median
From $99/mo
Get started →Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Direct Meds
Compounded semaglutide at $249/month
From $249/mo
Get started →He & She MD vs Medi-Weightloss: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.
