Question 1

Which works better for weight loss, Wegovy or Foundayo?

Accepted Answer

Wegovy recorded −14.9% TBWL / 68 wk (STEP-1, 2.4 mg); Foundayo recorded −11.1% body weight / 72 wk (ATTAIN-1, 17.2 mg). ⚠ These come from separate trials with different protocols and populations, so the gap between two numbers from two studies is weaker evidence than it looks. No head-to-head trial of this pair is on record here.

Question 2

Are Wegovy and Foundayo the same drug?

Accepted Answer

No. Wegovy is semaglutide and Foundayo is orforglipron — different molecules, and they work differently: Peptide GLP-1 receptor agonist (semaglutide) against Non-peptide small-molecule GLP-1 receptor agonist. Results with one do not predict results with the other.

Question 3

Is Wegovy or Foundayo cheaper?

Accepted Answer

On the manufacturers' own cash pricing: Wegovy at $349-$499/mo through the manufacturer's direct-pay program, Foundayo at Direct-pay pricing was still rolling out through 2026. ⚠ That is the list-price comparison, and it is not what most people pay. What you actually pay depends on whether your plan covers it, which formulary tier it sits in, and whether you have met your deductible — and for many people the honest comparison is between an insured copay and a cash-pay compounded alternative rather than between these two figures.

Question 4

How is each one taken?

Accepted Answer

Wegovy: 0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg weekly (5-step titration). Foundayo: 0.8 → 1.6 → 3 → 5.5 → 9 → 14.5 → 17.2 mg daily (7-step titration). Worth weighing honestly against your own habits — the best drug for you is partly the one you will still be taking in eight months, and a dosing routine that does not fit a life gets abandoned.

Question 5

What does a compounded version of each actually cost?

Accepted Answer

Across the 556 sellers in this register, the cheapest standing monthly cash prices we hold are semaglutide from $79 a month and orforglipron from $149 a month. ⛔ A compounded preparation is not the approved product: no agency has reviewed that specific preparation for safety, effectiveness or manufacturing quality, and the legal ground under compounding these molecules narrowed once the shortages closed. The price gap is real and so is the difference in oversight.

Question 6

Can I switch from Wegovy to Foundayo?

Accepted Answer

Yes, with a prescriber. Expect to re-titrate from the bottom of the new drug's ladder rather than starting where you left off: these are different molecules and tolerance to one does not transfer to the other. Both the old drug's washout and the new drug's schedule apply.

Question 7

Which one should I ask for?

Accepted Answer

That is a prescriber's call, and anyone answering it from a table is guessing. What a page like this can do is tell you what the trials measured, what the manufacturers charge, and where the evidence is still missing, so the conversation starts from the record rather than from an advertisement.

Field	Wegovy	Foundayo
Route & frequency	Subcutaneous injection, once weekly	Oral tablet, once daily — any time, with or without food
Mechanism	Peptide GLP-1 receptor agonist (semaglutide)	Non-peptide small-molecule GLP-1 receptor agonist
Weight loss (pivotal trial, max dose)	−14.9% TBWL / 68 wk (STEP-1, 2.4 mg)	−11.1% body weight / 72 wk (ATTAIN-1, 17.2 mg)
FDA-approved indication	Chronic weight management; CV risk reduction in obesity + CVD	Chronic weight management; type 2 diabetes
Dosing schedule	0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg weekly (5-step titration)	0.8 → 1.6 → 3 → 5.5 → 9 → 14.5 → 17.2 mg daily (7-step titration)
Food / timing requirement	None (injectable)	None — with or without food, any time of day
Whether a trial proved it prevents heart attacks and strokes	SELECT cut major cardiac events 20% in obesity without diabetes	None. No outcomes trial has reported
What it costs if you pay cash	$349-$499/mo through the manufacturer's direct-pay program	Direct-pay pricing was still rolling out through 2026

Wegovy vs Foundayo: Weekly Injection or Daily Pill

The verdict

Side-by-side comparison

What each one costs in the compounded market

Frequently asked questions