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Defy Medical vs Hims

Defy Medical and Hims sell different medications; this is what separates them.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Defy Medical logo

Defy Medical

4.1
★★☆☆☆2.1/5
Visit Defy Medical →
VS
Hims logo

Hims

6.8
★★★☆☆3.4/5

Best for: knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC

Visit Hims →

If you are choosing between Defy Medical and Hims, price alone will not settle it. Hims leads our six-part score, 6.8 to 4.1. One of the two has an FDA warning letter on record, covered below.

Defy Medical vs Hims price

Hims publishes $199 a month. Defy Medical does not post a GLP-1 price we can quote, so you would only learn its cost after an intake.

Medications and formats

Hims lists semaglutide and tirzepatide; Defy Medical does not name its drug.

On format, Defy Medical posts no priced format, while Hims prices compounded injections and brand-name pens.

If you want the FDA-approved brand rather than a compounded version, Hims is the only one of the two with a brand-name price.

Where each one treats patients

Defy Medical does not publish where it ships, and Hims lists 50 states.

Pricing

Defy Medical

Pricing not publicly listed.

Hims

StartingCompounded
$199/mo
semaglutide
StartingBrand-name
$299/mo
tirzepatide

Brand Zepbound from $299/mo medication-only; requires Hims Weight Loss Membership ($149/mo)

What each price covers

Hims' price also covers the medication itself, which Defy Medical does not claim.

Defy Medical does not say what its price includes.

Hims is silent on shipping and lab work.

That matters most for the drug: unless Defy Medical confirms otherwise, budget for medication on top of its listed price.

Defy Medical

Inclusions not disclosed.

Hims

Covered by the monthly price

Medication

In the price

Clinician visits

Charged on top

Shipping

Not stated

Lab work

Not stated

Coaching

Charged on top

Where each one scores higher

Overall, Hims scores 6.8 and Defy Medical 4.1 out of 10.

Defy Medical is stronger on support (5.0 vs 3.0).

Hims is stronger on effectiveness (10.0 vs 5.0), user experience (8.0 vs 3.0), trust & safety (7.0 vs 4.0) and accessibility (10.0 vs 5.0).

Value is within half a point.

How we score

Defy Medical

4.1/10

Overall

Hims

6.8/10

Value25%

3.0A
vs
B
3.0

Effectiveness25%

5.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
8.0

Trust & Safety15%

4.0A
vs
B
7.0

Accessibility10%

5.0A
vs
B
10.0

Support10%

5.0A
vs
B
3.0

FDA warning letters

The FDA sent Hims a warning letter dated September 9, 2025 (letter 716567), and it is still open.

Defy Medical has no FDA warning letter on record with us.

Features & Coverage

FeatureDefy MedicalHims
Starting PriceNot published$199/mo
Features✓8 features2 features
States AvailableNot disclosed50
Compounded—✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA Warning Letters✓None1 letter

About Defy Medical

Neither a price nor a list of covered states appears online. Hormone replacement made Defy Medical's name over many years, but the clinic writes GLP-1s too: semaglutide and tirzepatide as weekly shots, as orally disintegrating tablets and as liquid drops, with liraglutide taken daily by injection. Those drops and ODTs exist for patients who will not self-inject, or who live where shipping an injectable is restricted. Consults go deep, blood testing is comprehensive, and phlebotomy can come to you. Dr. Justin Saya is medical director.

Read our full Defy Medical review →

About Hims

Hims is a major men's telehealth brand. Its weight loss offering is compounded semaglutide on a 6-month plan.

Read our full Hims review →

Pros & Cons

Defy Medical

What we like

  • We found no FDA warning letters issued to Defy Medical

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

Hims

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication
  • Serves all 50 states
  • Names 4 pharmacies that fill its prescriptions, which most sellers do not

Watch-outs

  • Not included in the monthly price: clinician visits, coaching
  • The FDA has issued Hims a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Hims

Hims wins this one, 6.8 to 4.1, above all for knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC.

Choose Defy Medical if…

You want broader feature coverage.

Choose Hims if…

You want knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC and an opening price near $199 a month.

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Defy Medical vs Hims: FAQ

Only Hims publishes a price ($199 a month). Defy Medical quotes after sign-up.
No. Defy Medical lists no named drug; Hims lists semaglutide and tirzepatide.
Defy Medical does not publish where it ships; Hims lists 50 states. Confirm your state before paying.
Only Hims includes the medication itself.
Defy Medical has none. Hims has an open FDA warning letter from September 9, 2025.
No. Neither Defy Medical nor Hims pays us anything.

Or see the full category ranking.

Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.