Curex vs Signos
Curex and Signos both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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If you are choosing between Curex and Signos, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Curex leads our six-part score, 7.8 to 6.8. One of the two has an FDA warning letter on record, covered below.
Curex vs Signos price
Curex and Signos start at the same figure, $199 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $199 a month; tirzepatide costs the same at both, $199 a month.
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Curex lists 45 states, and Signos does not publish where it ships.
Pricing
Curex
ongoing anchored only as 'From $199/mo'; per-drug standard price no longer separately displayed; $49 = Summer Sale first month
ongoing anchored only as 'From $199/mo'; per-drug standard price no longer separately displayed; $149 = Summer Sale first month
Signos
Signos+ GLP-1 bundle (tirzepatide OR semaglutide) from $199/mo; includes CGM system
What each price covers
Both prices cover the medication itself and shipping.
Curex's price also covers the clinician visit, which Signos does not claim.
Curex is silent on coaching.
Signos is silent on the clinician visit, lab work and coaching.
Curex
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Charged on top
Coaching
Not stated
Signos
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Curex scores 7.8 and Signos 6.8 out of 10.
Curex is stronger on value (6.6 vs 4.5), accessibility (9.2 vs 5.0) and support (7.0 vs 4.5).
Signos is stronger on trust & safety (6.5 vs 5.5).
Effectiveness and user experience are within half a point.
Curex
7.8/10
Signos
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Curex a warning letter dated September 9, 2025 (letter 716821), and it is still open.
Signos has no FDA warning letter on record with us.
Features & Coverage
| Feature | Curex | Signos |
|---|---|---|
| Starting Price | $199/mo | $199/mo |
| Features | 5 features | ✓8 features |
| States Available | 45 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warning Letters | 1 letter | ✓None |
About Curex
Curex, Inc. sells compounded semaglutide at $149/mo and compounded tirzepatide at $199/mo, in injectable and oral dissolving tablet formats. It is LegitScript certified, charges no membership fee and is available in 43+ states. Offices are in Miami and New York City. The company started out in allergy immunotherapy.
Read our full Curex review →About Signos
Entry price is $199/mo, and that requires the 6-month plan; shipping is free and HSA/FSA cards work. What Signos+ adds to the prescription is hardware: an app plus a continuous glucose monitor cleared by the FDA, sitting alongside clinician-prescribed compounded semaglutide. Glucose readings arrive in real time with coaching attached, the stated aim being that a user grasps and then holds the loss. Its pitch is that this costs no more than the drug alone.
Read our full Signos review →Pros & Cons
Curex
What we like
- Semaglutide costs $199 a month, close to the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves 45 states
Watch-outs
- Not included in the monthly price: lab work
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Curex a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Signos
What we like
- Semaglutide costs $199 a month, close to the $185 median for compounded semaglutide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication and shipping
- We found no FDA warning letters issued to Signos
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Curex wins this one, 7.8 to 6.8, above all for an oral route if you will not self-inject. Signos fits better if compounded semaglutide at $199/month is your priority.
Choose Curex if…
You want an oral route if you will not self-inject and an opening price near $199 a month.
Choose Signos if…
You want compounded semaglutide at $199/month and an opening price near $199 a month.
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