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ARSYNL Rx vs CLYR Health

CLYR Health costs $4 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
ARSYNL Rx logo

ARSYNL Rx

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $233/month

Visit ARSYNL Rx →
VS
CLYR Health logo

CLYR Health

7.0
★★★★☆3.5/5

Best for: compounded semaglutide at $229/month

Visit CLYR Health →

If you are choosing between ARSYNL Rx and CLYR Health, the first difference is cost: CLYR Health is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. CLYR Health leads our six-part score, 7.0 to 6.7.

ARSYNL Rx vs CLYR Health price

CLYR Health is the cheaper way in: $229 a month against $233 a month at ARSYNL Rx. That is $4 less each month (2% lower), or about $48 over a year of treatment.

Drug by drug: Semaglutide is cheaper at CLYR Health ($229 a month vs $233 a month); tirzepatide is cheaper at CLYR Health ($249 a month vs $366.33 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Neither ARSYNL Rx nor CLYR Health publishes the states it serves, so enter your state at the very start of each sign-up.

Pricing

ARSYNL Rx

Doctor-led semaglutide plan, monthly (with vitamin B12)Compounded
$233/mo
semaglutide

"Doctor-Led Semaglutide Weight Loss Plans Starting at $233.00/Month". First-time orders advertise $50 off with code NEWROOTS50.

Doctor-led tirzepatide plan, monthly (with vitamin B12)Compounded
$366.33/mo
tirzepatide

"Doctor-Led Tirzepatide Weight Loss Plans Starting at $366.33/Month".

CLYR Health

Compounded semaglutide + B12Compounded
$229/mo
semaglutide

Flat any-dose $229/mo; 3-month prepay $189/mo ($567 billed once)

Compounded tirzepatide + B12Compounded
$249/mo
tirzepatide

$249/mo standard dose (up to 3mL); 3-month prepay $199/mo; higher dose 4-8mL $349/mo

What each price covers

Both prices cover the clinician visit and the medication itself.

ARSYNL Rx's price also covers shipping, which CLYR Health does not claim.

ARSYNL Rx is silent on lab work and coaching.

CLYR Health is silent on shipping, lab work and coaching.

ARSYNL Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

CLYR Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, CLYR Health scores 7.0 and ARSYNL Rx 6.7 out of 10.

ARSYNL Rx is stronger on support (7.0 vs 5.5).

CLYR Health is stronger on value (5.0 vs 3.3).

Effectiveness, user experience, trust & safety and accessibility are within half a point.

How we score

ARSYNL Rx

6.7/10

Overall

CLYR Health

7.0/10

Value25%

3.3A
vs
B
5.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
6.5

Accessibility10%

5.0A
vs
B
5.0

Support10%

7.0A
vs
B
5.5

FDA warning letters

Neither ARSYNL Rx nor CLYR Health has an FDA warning letter on record with us.

Features & Coverage

FeatureARSYNL RxCLYR Health
Starting Price$233/mo✓$229/mo
Features✓8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About ARSYNL Rx

Prices only surface on individual product pages, once a therapy has been picked. ARSYNL Rx was founded by a veteran and runs several services: compounded semaglutide and compounded tirzepatide for weight loss, including a tirzepatide hypospray that needs no needle, plus longevity care, sexual health, testosterone therapy and hair restoration. A clinician writes the prescription and the package arrives discreetly at home.

Read our full ARSYNL Rx review →

About CLYR Health

Any dose, one price: compounded semaglutide with B12 from $229/mo and compounded tirzepatide with B12 from $249/mo, with 3-month prepay bringing the effective rate down. Oral GLP-1 options and brand Zepbound appear on the list as well. Wellness, longevity and sexual-health treatments share the storefront of this Florida telehealth pharmacy, which is LegitScript Certified and has a named 503A pharmacy behind fulfillment.

Read our full CLYR Health review →

Pros & Cons

ARSYNL Rx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to ARSYNL Rx

Watch-outs

  • Semaglutide costs $233 a month, 26% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $366.33 a month, 47% above the $250 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

CLYR Health

What we like

  • Tirzepatide costs $249 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to CLYR Health

Watch-outs

  • Semaglutide costs $229 a month, 24% above the $185 median for compounded semaglutide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: CLYR Health

CLYR Health wins this one, 7.0 to 6.7, above all for compounded semaglutide at $229/month. It also costs $4 less each month than ARSYNL Rx. ARSYNL Rx fits better if compounded semaglutide at $233/month is your priority.

Choose ARSYNL Rx if…

You want compounded semaglutide at $233/month and an opening price near $233 a month.

Choose CLYR Health if…

You want compounded semaglutide at $229/month and an opening price near $229 a month.

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7.8

Oak

Semaglutide at $119/month, 37% below the typical price

9.4

Trimi Health

Knowing which pharmacy fills the vial: it names VialsRx

6.4

ShedRx

Oral orforglipron alongside the injectables

ARSYNL Rx vs CLYR Health: FAQ

CLYR Health. It starts at $229 a month; ARSYNL Rx starts at $233 a month, $4 more per month.
Yes, both sell semaglutide and tirzepatide.
ARSYNL Rx does not publish where it ships; CLYR Health does not publish where it ships. Confirm your state before paying.
Both include the clinician visit and the medication itself. Only ARSYNL Rx includes shipping.
ARSYNL Rx has none. CLYR Health has none.
No. Neither ARSYNL Rx nor CLYR Health pays us anything.

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