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ARSYNL Rx vs AVARA Rx

AVARA Rx costs $4 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
ARSYNL Rx logo

ARSYNL Rx

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $233/month

Visit ARSYNL Rx →
VS
AVARA Rx logo

AVARA Rx

6.0
★★★☆☆3/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit AVARA Rx →

If you are choosing between ARSYNL Rx and AVARA Rx, the first difference is cost: AVARA Rx is $4 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. ARSYNL Rx leads our six-part score, 6.7 to 6.0.

ARSYNL Rx vs AVARA Rx price

AVARA Rx is the cheaper way in: $229 a month against $233 a month at ARSYNL Rx. That is $4 less each month (2% lower), or about $48 over a year of treatment.

Drug by drug: Semaglutide is cheaper at AVARA Rx ($229 a month vs $233 a month); tirzepatide is cheaper at AVARA Rx ($279 a month vs $366.33 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

ARSYNL Rx does not publish where it ships, and AVARA Rx lists 50 states.

Pricing

ARSYNL Rx

Doctor-led semaglutide plan, monthly (with vitamin B12)Compounded
$233/mo
semaglutide

"Doctor-Led Semaglutide Weight Loss Plans Starting at $233.00/Month". First-time orders advertise $50 off with code NEWROOTS50.

Doctor-led tirzepatide plan, monthly (with vitamin B12)Compounded
$366.33/mo
tirzepatide

"Doctor-Led Tirzepatide Weight Loss Plans Starting at $366.33/Month".

AVARA Rx

Starting tiercompounded injection
$229/mo
semaglutide
Starting tiercompounded injection
$279/mo
tirzepatide

What each price covers

ARSYNL Rx's price also covers the clinician visit, the medication itself and shipping, which AVARA Rx does not claim.

ARSYNL Rx is silent on lab work and coaching.

AVARA Rx does not say what its price includes.

That matters most for the drug: unless AVARA Rx confirms otherwise, budget for medication on top of its listed price.

ARSYNL Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

AVARA Rx

Inclusions not disclosed.

Where each one scores higher

Overall, ARSYNL Rx scores 6.7 and AVARA Rx 6.0 out of 10.

ARSYNL Rx is stronger on user experience (8.0 vs 3.0), trust & safety (6.5 vs 5.0) and support (7.0 vs 5.0).

AVARA Rx is stronger on accessibility (10.0 vs 5.0).

Value and effectiveness are within half a point.

How we score

ARSYNL Rx

6.7/10

Overall

AVARA Rx

6.0/10

Value25%

3.3A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
3.0

Trust & Safety15%

6.5A
vs
B
5.0

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
5.0

FDA warning letters

Neither ARSYNL Rx nor AVARA Rx has an FDA warning letter on record with us.

Features & Coverage

FeatureARSYNL RxAVARA Rx
Starting Price$233/mo✓$229/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes—
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About ARSYNL Rx

Prices only surface on individual product pages, once a therapy has been picked. ARSYNL Rx was founded by a veteran and runs several services: compounded semaglutide and compounded tirzepatide for weight loss, including a tirzepatide hypospray that needs no needle, plus longevity care, sexual health, testosterone therapy and hair restoration. A clinician writes the prescription and the package arrives discreetly at home.

Read our full ARSYNL Rx review →

About AVARA Rx

Compounded semaglutide opens at $229/month, compounded tirzepatide at $279/month, cash only. Consultations for the branded drugs Wegovy, Zepbound and Foundayo are offered as well, and HRT, TRT and longevity products fill out the menu. AVARA Rx puts both the pharmacy it uses and the clinical network behind it on record, which sits well above the transparency floor in this category. All 50 states are covered.

Read our full AVARA Rx review →

Pros & Cons

ARSYNL Rx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to ARSYNL Rx

Watch-outs

  • Semaglutide costs $233 a month, 26% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $366.33 a month, 47% above the $250 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

AVARA Rx

What we like

  • Serves all 50 states
  • We found no FDA warning letters issued to AVARA Rx

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: ARSYNL Rx

ARSYNL Rx wins this one, 6.7 to 6.0, above all for compounded semaglutide at $233/month. AVARA Rx undercuts it by $4 a month, so if the monthly bill is what decides it, AVARA Rx is the pick. AVARA Rx fits better if coverage in all 50 states, which most sellers will not confirm is your priority.

Choose ARSYNL Rx if…

You want compounded semaglutide at $233/month and an opening price near $233 a month.

Choose AVARA Rx if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $229 a month.

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ARSYNL Rx vs AVARA Rx: FAQ

AVARA Rx. It starts at $229 a month; ARSYNL Rx starts at $233 a month, $4 more per month.
Yes, both sell semaglutide and tirzepatide.
ARSYNL Rx does not publish where it ships; AVARA Rx lists 50 states. Confirm your state before paying.
Only ARSYNL Rx includes the clinician visit, the medication itself and shipping.
ARSYNL Rx has none. AVARA Rx has none.
No. Neither ARSYNL Rx nor AVARA Rx pays us anything.

Or see the full category ranking.