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CLYR Health vs EdgeRx

CLYR Health and EdgeRx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
CLYR Health logo

CLYR Health

7.0
★★★★☆3.5/5

Best for: compounded semaglutide at $229/month

Visit CLYR Health →
VS
EdgeRx logo

EdgeRx

7.8
★★★★☆3.9/5

Best for: knowing which pharmacy fills the vial: it names Strive Pharmacy

Visit EdgeRx →

If you are choosing between CLYR Health and EdgeRx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. EdgeRx leads our six-part score, 7.8 to 7.0.

CLYR Health vs EdgeRx price

CLYR Health and EdgeRx start at the same figure, $229 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $229 a month; tirzepatide is cheaper at CLYR Health ($249 a month vs $299 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

CLYR Health does not publish where it ships, and EdgeRx lists 46 states.

Pricing

CLYR Health

Compounded semaglutide + B12Compounded
$229/mo
semaglutide

Flat any-dose $229/mo; 3-month prepay $189/mo ($567 billed once)

Compounded tirzepatide + B12Compounded
$249/mo
tirzepatide

$249/mo standard dose (up to 3mL); 3-month prepay $199/mo; higher dose 4-8mL $349/mo

EdgeRx

Once-weekly subcutaneous injection, variable-dose vials, titrated by physician. Not currently available for purchase — waitlist only as of Aug 2026.Compounded
$229/mo
semaglutide

Formulated with glycine + B12; compounded by Strive Pharmacy (503A). Protocol page states 'The Semaglutide protocol is not currently available for purchase.'

Once-weekly subcutaneous injection, variable-dose vials, titrated by physician. Not currently available for purchase — waitlist only as of Aug 2026.Compounded
$299/mo
tirzepatide

Formulated with glycine + B12; compounded by Strive Pharmacy (503A). Protocol page states 'The Tirzepatide protocol is not currently available for purchase.'

What each price covers

Both prices cover the clinician visit and the medication itself.

EdgeRx's price also covers shipping, which CLYR Health does not claim.

CLYR Health is silent on shipping, lab work and coaching.

EdgeRx is silent on lab work and coaching.

CLYR Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

EdgeRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, EdgeRx scores 7.8 and CLYR Health 7.0 out of 10.

CLYR Health is stronger on value (5.0 vs 3.7).

EdgeRx is stronger on trust & safety (10.0 vs 6.5), accessibility (9.4 vs 5.0) and support (7.0 vs 5.5).

Effectiveness and user experience are within half a point.

How we score

CLYR Health

7.0/10

Overall

EdgeRx

7.8/10

Value25%

5.0A
vs
B
3.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
10.0

Accessibility10%

5.0A
vs
B
9.4

Support10%

5.5A
vs
B
7.0

FDA warning letters

Neither CLYR Health nor EdgeRx has an FDA warning letter on record with us.

Features & Coverage

FeatureCLYR HealthEdgeRx
Starting Price$229/mo$229/mo
Features6 features✓8 features
States AvailableNot disclosed46
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted—✓ Yes
FDA Warning LettersNoneNone

About CLYR Health

Any dose, one price: compounded semaglutide with B12 from $229/mo and compounded tirzepatide with B12 from $249/mo, with 3-month prepay bringing the effective rate down. Oral GLP-1 options and brand Zepbound appear on the list as well. Wellness, longevity and sexual-health treatments share the storefront of this Florida telehealth pharmacy, which is LegitScript Certified and has a named 503A pharmacy behind fulfillment.

Read our full CLYR Health review →

About EdgeRx

Nothing can be bought yet. Prices and descriptions for both GLP-1 injections are up, but the protocols sit behind a waitlist and checkout has not opened for any of them. Strive Pharmacy, the sole 503A compounder named, makes the Tirzepatide and Semaglutide shots, each formulated with B12 and glycine to preserve muscle. Sexual health, hair, cognition and recovery form four further outcome categories at EdgeRx Health, LLC. Physician review is priced in, payment is cash, and Truemed carries HSA/FSA.

Read our full EdgeRx review →

Pros & Cons

CLYR Health

What we like

  • Tirzepatide costs $249 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to CLYR Health

Watch-outs

  • Semaglutide costs $229 a month, 24% above the $185 median for compounded semaglutide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

EdgeRx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Serves 46 states
  • Names Strive Pharmacy as the pharmacy that fills its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to EdgeRx

Watch-outs

  • Semaglutide costs $229 a month, 24% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: EdgeRx

EdgeRx wins this one, 7.8 to 7.0, above all for knowing which pharmacy fills the vial: it names Strive Pharmacy. CLYR Health fits better if compounded semaglutide at $229/month is your priority.

Choose CLYR Health if…

You want compounded semaglutide at $229/month and an opening price near $229 a month.

Choose EdgeRx if…

You want knowing which pharmacy fills the vial: it names Strive Pharmacy and an opening price near $229 a month.

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7.8

Oak

Semaglutide at $119/month, 37% below the typical price

9.4

Trimi Health

Knowing which pharmacy fills the vial: it names VialsRx

6.4

ShedRx

Oral orforglipron alongside the injectables

CLYR Health vs EdgeRx: FAQ

Neither on the entry price: CLYR Health and EdgeRx both start at about $229 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
CLYR Health does not publish where it ships; EdgeRx lists 46 states. Confirm your state before paying.
Both include the clinician visit and the medication itself. Only EdgeRx includes shipping.
CLYR Health has none. EdgeRx has none.
No. Neither CLYR Health nor EdgeRx pays us anything.

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