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10rx vs tru Weight Loss

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

8.1
★★★★4.1/5

Best for: semaglutide at $99.67/month, 47% under the register median

Visit 10rx
VS

tru Weight Loss

6.4
★★★☆☆3.2/5

Best for: compounded semaglutide at $299/month

Visit tru Weight Loss

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, 10rx opens cheaper — $99.67/mo against $299, and 10rx finishes ahead, 8.1 to 6.4. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

tru Weight Loss

All doses (flat)Compounded
$299/mo
semaglutide

3-month minimum then cancel anytime; includes consult, labs, coaching, and delivery

All doses (flat)Compounded
$399/mo
tirzepatide

3-month minimum then cancel anytime; includes consult, labs, coaching, and delivery

What’s included

10rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

tru Weight Loss

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

8.1/10

Overall

tru Weight Loss

6.4/10

Value25%

9.6A
vs
B
2.1

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

5.5A
vs
B
6.5

Accessibility10%

5.0A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

Features & Coverage

Feature10rxtru Weight Loss
Starting Price$99.67/mo$299/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx sets flat monthly rates on compounded GLP-1: semaglutide at $99.67, tirzepatide at $149.67, with NAD+ and sermorelin sold separately for energy and recovery. A free health quiz online reaches a board-certified telehealth doctor, who reads your history before writing anything, and licensed pharmacy partners handle discreet delivery. The company states it reaches every one of the 50 states. What it does not state is its operating company, its pharmacies, or any terms page.

Read our full 10rx review →

About tru Weight Loss

A 3-month minimum applies, and after that you can cancel at will, at flat rates of 299 dollars per month for semaglutide and 399 dollars per month for tirzepatide. Behavioral and nutritionist coaching, delivery of the drug, a plan built for you, lab work and the telehealth consult are all absorbed by that fee. US-licensed compounding pharmacies ship the compounded tirzepatide and semaglutide. Neha Grover, MD directs truhealthnow out of a Germantown, Maryland clinic. FSA, HSA and insurance are all refused.

Read our full tru Weight Loss review →

Pros & Cons

10rx

What we like

  • Semaglutide at $99.67 a month, 47% below the $189 median for the same drug and form across this register
  • Tirzepatide at $149.67 a month, 44% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

tru Weight Loss

What we like

  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Semaglutide at $299 a month, 58% above the $189 register median for the same drug and form
  • Tirzepatide at $399 a month, 49% above the $267 register median for the same drug and form
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: 10rx

10rx takes it, 8.1 against 6.4, and it is especially strong on semaglutide at $99.67/month, 47% under the register median. tru Weight Loss is no weak second and may fit you better on compounded semaglutide at $299/month.

Choose 10rx if…

You want semaglutide at $99.67/month, 47% under the register median and an opening price near $99.67 a month.

Choose tru Weight Loss if…

You want compounded semaglutide at $299/month and an opening price near $299 a month.

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Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

8.2

YourEra

Semaglutide at $99/month, 63% under the register median

8.8

Gala

Moving between compounded and brand without changing seller

9.4

Trimi Health

Knowing which pharmacy fills the vial — it names VialsRx

10rx vs tru Weight Loss: FAQ

Glossary

The words sellers use, defined. Tap any term.

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