Best Epitalon Providers in 2026: Ranked and Reviewed
Epithalamin, an extract first isolated from the pineal gland, is the basis for Epitalon (also spelled epithalon), a synthetic four-amino-acid peptide. Among longevity peptides it is one of the more studied for activating telomerase, which rebuilds the protective caps on chromosomes. Human cell lines grown in the lab have been pushed past their normal division limit with it, and trials in older adults, run in Russia, reported lower mortality and longer telomeres across long-term follow-up. Weigh that against where it comes from: decades of Russian institutional studies, never independently validated elsewhere, with no Western clinical-trial evidence to match. Since October 28, 2026, an interim HHS policy says HHS does not intend to take enforcement action against state-licensed 503A pharmacies that compound it as an injection, in intermittent courses, under strict conditions. The current status is below.
7 providers compared
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7 epitalon providers compared · independently scored against our six-factor methodology.
Compare the top providers at a glance
Every row carries a logo, our editorial rating, price, the medications prescribed, and where the seller ships. Scan down a column and the list shortens fast.
- ★ Editor's Pick
single-ingredient epitalon by prescription (injection)
From /moCheck pricingCoverageCheck intakeMedicationsBPC-157EpitalonGHK-CuKPVMOTS-cNAD+SemaxSermorelinTB-500 - Nationwide Coverage
single-ingredient epitalon by prescription (subcutaneous injection)
From /moCheck pricingCoverage50 statesMedicationsBPC-157CJC-1295 / IpamorelinEpitalonGHK-CuGlutathioneMOTS-cNAD+retatrutideSemaxSermorelinTB-500 single-ingredient epitalon by prescription (subcutaneous injection, intramuscular injection)
From /moCheck pricingCoverage45 states + DCMedicationsBPC-157EpitalonGlutathioneKPVMOTS-cNAD+SemaxSermorelinTB-500
Show 4 moreShow fewer
single-ingredient epitalon by prescription (subcutaneous injection)
From /moCheck pricingCoverageCheck intakeMedicationsBPC-157EpitalonGlutathioneKPVMOTS-cNAD+SemaxSermorelinTB-500single-ingredient epitalon by prescription (subcutaneous injection)
From /moCheck pricingCoverageCheck intakeMedicationsCJC-1295 / IpamorelinDSIPEpitalonGHK-CuIpamorelinMOTS-cNAD+SelankSemaxSermorelinTesamorelinsingle-ingredient epitalon by prescription (subcutaneous injection)
From /moCheck pricingCoverage27 states + DCMedicationsBPC-157CJC-1295 / IpamorelinEpitalonGHK-CuGlutathioneGonadorelinIpamorelinKPVMOTS-cNAD+PT-141SemaxSermorelinTB-500Tesamorelinsingle-ingredient epitalon by prescription (subcutaneous injection)
From /moCheck pricingCoverage1 stateMedications5-Amino-1MQBPC-157EpitalonGHK-CuKPVMOTS-cNAD+PT-141SemaxSermorelinTB-500Tesamorelin
| Provider | Rating | From /mo | Medications | Coverage | |
|---|---|---|---|---|---|
★ Editor's Pick single-ingredient epitalon by prescription (injection) | Check pricing | BPC-157EpitalonGHK-CuKPVMOTS-cNAD+SemaxSermorelinTB-500 | Check intake | Visit → | |
Nationwide Coverage single-ingredient epitalon by prescription (subcutaneous injection) | Check pricing | BPC-157CJC-1295 / IpamorelinEpitalonGHK-CuGlutathioneMOTS-cNAD+retatrutideSemaxSermorelinTB-500 | 50 states | Visit → | |
 single-ingredient epitalon by prescription (subcutaneous injection, intramuscular injection) | Check pricing | BPC-157EpitalonGlutathioneKPVMOTS-cNAD+SemaxSermorelinTB-500 | 45 states + DC | Visit → | |
 single-ingredient epitalon by prescription (subcutaneous injection) | Check pricing | BPC-157EpitalonGlutathioneKPVMOTS-cNAD+SemaxSermorelinTB-500 | Check intake | Visit → | |
 single-ingredient epitalon by prescription (subcutaneous injection) | Check pricing | CJC-1295 / IpamorelinDSIPEpitalonGHK-CuIpamorelinMOTS-cNAD+SelankSemaxSermorelinTesamorelin | Check intake | Visit → | |
 single-ingredient epitalon by prescription (subcutaneous injection) | Check pricing | BPC-157CJC-1295 / IpamorelinEpitalonGHK-CuGlutathioneGonadorelinIpamorelinKPVMOTS-cNAD+PT-141SemaxSermorelinTB-500Tesamorelin | 27 states + DC | Visit → | |
LL LiveNow Longevitysingle-ingredient epitalon by prescription (subcutaneous injection) | Check pricing | 5-Amino-1MQBPC-157EpitalonGHK-CuKPVMOTS-cNAD+PT-141SemaxSermorelinTB-500Tesamorelin | 1 state | Visit → |
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What this ranking checks
An interim HHS policy dated October 28, 2026 says HHS does not intend to take enforcement action against state-licensed pharmacies, federal facilities or licensed physicians that compound Epitalon under set conditions, until a final rule settles whether Epitalon goes on the 503A bulks list. The policy is interim enforcement discretion, and HHS’s Federal Register notice of October 30, 2026 calls it a draft that is not binding. It does not approve the peptide or add it to the 503A bulks list, it covers 503A pharmacies and physicians only (not 503B outsourcing facilities or research-use-only sellers), and HHS can narrow or withdraw it if safety or quality problems surface. The conditions: a patient-specific prescription; Epitalon acetate as the only active ingredient, with no blends; subcutaneous or intramuscular injection only, dispensed in intermittent courses; the raw powder must be made at an FDA-registered plant and tested, on its certificate of analysis, for identity, strength, purity, endotoxin, microbes, heavy metals and other impurities; adverse events and quality problems go to FDA MedWatch; and the label must say the product is compounded and not for resale.
What our ranking checks: that the seller's own website, read on November 5, 2026, offers Epitalon as a single ingredient, by prescription, in a route the policy covers. Sellers whose pages offer it only in a blend, or in a form outside those routes, are not ranked.
What no website read can show: which 503A pharmacy fills the prescription, the certificate of analysis and the source of the raw powder, whether the label says the product is compounded and not for resale, whether adverse events are reported to FDA MedWatch, and which device comes with it. Ask the seller for those before you pay. Being ranked here is not a finding that a seller meets the policy.
What each seller’s own page showed on November 5, 2026
- EnhancedRoute: injectionPrice as listed: $119 for 1 month; 3-month plan $327 billed every 3 months ($109/mo)
- ElitePhysiqMDRoute: subcutaneous injectionPrice as listed: $163.00 every 3 months ($146.70 with subscribe-and-save)
- New TidesRoute: subcutaneous injection, intramuscular injectionPrice as listed: not published
- Scripts Rx DirectRoute: subcutaneous injectionPrice as listed: Injection 2 mg/mL: $179 for 1 month, $479 for 3 months ($160/mo)
- Bridgeside TelehealthRoute: subcutaneous injectionPrice as listed: $300 first month, consultation included
- RxPepsDirectRoute: subcutaneous injectionPrice as listed: $80 per 5mL vial (10mg total); a high-dose version is also listed
- LiveNow LongevityRoute: subcutaneous injectionPrice as listed: not published
Detailed Reviews
About the prices below: every dollar figure inside these provider summaries belongs to that clinic’s GLP‑1 weight-loss program. None is a Epitalon price. For Epitalon itself, read the price each seller’s own page listed, under “What this ranking checks” above. “Check pricing” in the tables means we hold no monthly figure for that seller that compares like for like, since many quote per vial, per capsule or per multi-month protocol.
Enhanced
Best for: single-ingredient epitalon by prescription (injection)
Enhanced is the consumer health line of Enhanced Group, the publicly traded company behind the Enhanced Games sports competition. Independent clinicians prescribe compounded semaglutide and tirzepatide through it, plus microdose plans from $59 a month on a 12-month plan, testosterone and peptides including BPC-157, TB-500, MOTS-c, KPV, epitalon and semax. Semaglutide costs $129 a month, or $89 a month on a 12-month plan paid up front; tirzepatide costs $169, or $129 on the same terms.
Score Breakdown
Pros
- ✓Semaglutide costs $129 a month, 35% below the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $169 a month, 37% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price stays the same as your dose goes up
- ✓The monthly price includes the medication, clinician visits and shipping
- ✓Names 4 pharmacies that fill its prescriptions, which most sellers do not
- ✓We found no FDA warning letters issued to Enhanced
Cons
- ✗Confirm it serves your state before you start the intake
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
ElitePhysiqMD
Best for: single-ingredient epitalon by prescription (subcutaneous injection)
ElitePhysiqMD, now at a new web address, sells compounded semaglutide at $219 for 4 weeks and tirzepatide from $249, rising with dose to $389. Each one-time order adds a $49 video visit and, after the first order, $30 shipping. Members pay 10% less per refill and no visit or shipping fees, but membership costs $89 a month. A board-certified internist, Hridayesh Nat, MD, is the named medical director.
Score Breakdown
Pros
- ✓Semaglutide costs $219 a month, close to the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $249 a month, 7% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication, clinician visits and shipping
- ✓Serves all 50 states
- ✓We found no FDA warning letters issued to ElitePhysiqMD
- ✓A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Cons
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
- ✗Its menu lists retatrutide, which FDA says cannot be used in compounding under federal law and has not been found safe and effective for any condition
New Tides
Best for: single-ingredient epitalon by prescription (subcutaneous injection, intramuscular injection)
Score breakdown, pros and cons
New Tides is a physician-led telehealth practice that prescribes compounded semaglutide and tirzepatide and may also prescribe nine peptides, including the six named in the October 2026 HHS peptide policy. Nothing is charged at sign-up: the card you save is charged only when a physician sends a prescription, and there is no subscription. Semaglutide is $200 and tirzepatide $250 per prescription, the same at every dose, with the physician visit, medication and shipping included.
Score Breakdown
Pros
- ✓Semaglutide costs $200 a month, close to the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $250 a month, 7% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication, clinician visits and shipping
- ✓Serves 45 states and DC
- ✓We found no FDA warning letters issued to New Tides
Cons
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Scripts Rx Direct
Best for: single-ingredient epitalon by prescription (subcutaneous injection)
Score breakdown, pros and cons
Scripts Rx Direct is an online clinic that prescribes compounded semaglutide and tirzepatide and sells a catalog of compounded peptides, including all six named in the October 2026 HHS peptide policy, plus NAD+, sermorelin and glutathione. Every listing shows its price before checkout, and a clinician licensed in your state reviews an intake that follows payment. One-month offers list semaglutide at $200 and tirzepatide at $247.
Score Breakdown
Pros
- ✓Semaglutide costs $200 a month, close to the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $247 a month, 8% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes clinician visits
- ✓We found no FDA warning letters issued to Scripts Rx Direct
Cons
- ✗Confirm it serves your state before you start the intake
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Bridgeside Telehealth
Best for: single-ingredient epitalon by prescription (subcutaneous injection)
Score breakdown, pros and cons
Bridgeside Telehealth is a telehealth clinic, run under Texas law, that books a scheduled virtual consultation before prescribing semaglutide or tirzepatide, and it also prescribes about a dozen compounded peptides. Its drug pages list a $99 consultation and GLP-1 programs starting at $275 a month, with higher tirzepatide doses at $370, though other pages on the same site quote $199 and $100 to $200. Prescriptions go to unnamed 503A or 503B compounding pharmacies.
Score Breakdown
Pros
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓We found no FDA warning letters issued to Bridgeside Telehealth
Cons
- ✗Tirzepatide costs $370 a month, 38% above the $269 median for compounded tirzepatide across the sellers we compare
- ✗Not included in the monthly price: clinician visits
- ✗Confirm it serves your state before you start the intake
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
How we rank, and what counts as “legit”
Scoring for every provider on this page runs against our published six-factor rubric[1]: value, effectiveness, user experience, trust & safety, accessibility and support.
Each of Wegovy, Zepbound, Ozempic and Mounjaro holds its own separate FDA approval under its own NDA number[4][5]. Published Phase 3 efficacy for semaglutide at 2.4 mg (~14.9% mean weight loss across 68 weeks) comes from STEP 1[6]; those for tirzepatide (~20.9% at the 15 mg dose over 72 weeks) come from SURMOUNT-1[7]. In 2025 the SURMOUNT-5 head-to-head set the two against each other[8].
How much of an anti-obesity medication is covered varies widely between state Medicaid programs and between commercial plans[9][10]. Under IRS Publication 502, compounded GLP-1s and brand-name ones alike are generally FSA/HSA eligible where a prescription exists[11].
Frequently Asked Questions
Sources & methodology — as of November 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 5.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 8.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
- 9.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 10.CMS — Medicaid prescription drug coverage policy (state-by-state)— Centers for Medicare & Medicaid Services.
- 11.IRS Publication 502 — Medical and Dental Expenses (HSA/FSA eligibility)— Internal Revenue Service.