Cost Plus Drugs Review
Semaglutide GLP-1 weight-loss telehealth · Independently scored 7.8/10
Best for: coverage in all 50 states, which most sellers will not confirm
Cost Plus Drugs falls below our bar on disclosure. Read the breakdown below before you give it money.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Covered by the monthly price
Medication
Not stated
Clinician visits
Not stated
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
Prices checked July 2026
Cost Plus Drugs is Mark Cuban's transparent-pricing online pharmacy. It sells branded Ozempic at the wholesale acquisition cost plus a 15% markup and a flat $5 pharmacy fee, a margin formula it discloses publicly. There is no telehealth intake; this is pharmacy fulfillment only, shipping to all 50 states. Telehealth platforms that route brand-name semaglutide through similar discount channels are a separate category.
Is Cost Plus Drugs legit?
Yes. Cost Plus Drugs is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 7.8/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Cost Plus Drugs promo or coupon code?
We know of no promo or coupon code for Cost Plus Drugs. Its listed price is $279 a month. Coupon sites advertising "Cost Plus Drugs discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how Cost Plus Drugs compares on our rankings of the best semaglutide providers.
Vetted alternatives to Cost Plus Drugs
Trimi Health
Best for: knowing which pharmacy fills the vial: it names VialsRx
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
Cost Plus Drugs at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Ozempic
- Starting price
- $279/mo
- Availability
- All 50 states
- FDA status
- No FDA warning letters found
How Cost Plus Drugs scores
Six columns, each one computed from something Cost Plus Drugs has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
10.0/10$279/month is 72% below the $997 median for brand-name semaglutide across the sellers we compare.
Effectiveness25%
9.0/10Dispenses semaglutide, including the FDA-approved product. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
5.0/10Where this seller first shows a price is not known, so sign-up is held at the midpoint.
Trust & Safety15%
5.0/10No pharmacy is named for its prescriptions. There is no confirmed price before the medical intake. It lists the states it serves.
Accessibility10%
10.0/10Serves 50 of 50 states.
Support10%
5.0/10States too little about what the monthly cost covers to score the bundle. Held at the midpoint rather than assumed.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Cost Plus Drugs
Last checked July 2026- Checked the listed price across 1 dose or plan tier
- Checked state coverage: all 50
- Checked FDA warning letters for Cost Plus Drugs
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
GLP-1 medications Cost Plus Drugs offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
Check the price yourself before you pay
Every figure here was read off Cost Plus Drugs's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Semaglutide costs $279 a month, 72% below the $997 median for brand-name semaglutide across the sellers we compare
- Serves all 50 states
- We found no FDA warning letters issued to Cost Plus Drugs
Against it
- Ask which pharmacy fills the prescription before you pay, so you can check its license
What Cost Plus Drugs charges
Cost Plus Drugs charges $279/month. That sits at the affordable end of what we see.
- Brand-name semaglutide: $279/month
For brand-name semaglutide, the median across the sellers we compare is $997/month, so Cost Plus Drugs' $279 is genuinely below the middle, not just advertised that way.
MangoRx, at about $299/month, is the closest like-for-like alternative we review.
What Cost Plus Drugs dispenses
Cost Plus Drugs prescribes semaglutide (approved as Wegovy and Ozempic). That is among the best-evidenced options in this class. These are FDA-approved brand-name products rather than compounded preparations, which is the more expensive route and the one where what is in the pen has been reviewed.
Safety and disclosure
Cost Plus Drugs tells you that it treats patients in all 50 states. We found no FDA warning letters issued to Cost Plus Drugs. How we weigh oversight, disclosure and price is set out in our scoring methodology.
It fits if
- the lowest standing monthly cost is what you are solving for
- you need access wherever you live
- you want to try routing the cost through your insurance
Our read
Cost Plus Drugs competes on price: $279/month. The catch is disclosure, which is why Cost Plus Drugs scores low on Trust & Safety: settle the pharmacy and pricing questions above before the price decides for you.
The Bottom Line
Cost Plus Drugs falls below our bar on disclosure. Read the breakdown below before you give it money.
Before you pay Cost Plus Drugs
Starting at $279 a month. Check today's price, then start the intake.
Where Cost Plus Drugs is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.
- If the standing monthly cost is what decides it, consider Sesame Care (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare Cost Plus Drugs head to head
The sellers closest to Cost Plus Drugs on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Cost Plus Drugs review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of July 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
See Cost Plus Drugs's current pricing
Plans start at $279 a month. Whether you qualify is a clinician's decision, made after your intake.