TrimRx vs Wisp
Wisp costs $80 less a month, and both sell semaglutide and tirzepatide.
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If you are choosing between TrimRx and Wisp, the first difference is cost: Wisp is $80 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. TrimRx leads our six-part score, 7.2 to 6.5.
TrimRx vs Wisp price
Wisp is the cheaper way in: $99 a month against $179 a month at TrimRx. That is $80 less each month (45% lower), or about $960 over a year of treatment.
Drug by drug: Semaglutide is cheaper at TrimRx ($179 a month vs $225 a month); tirzepatide is cheaper at Wisp ($99 a month vs $259 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and brand-name pens.
Where each one treats patients
Neither TrimRx nor Wisp publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
TrimRx
GLP-1 starts at $179. The homepage shows a $299.00 list price struck through to $179.00 for the first month, and an email sign-up offer promises '$120 OFF' your first order, for a first month as low as $135. Multi-month bundles (formerly $209/$191/$174) are no longer published; plan prices appear only after the intake questionnaire.
The GLP-1 + GIP plan, which contains tirzepatide, starts at $259, down from an earlier $279 limited offer. Multi-month bundles (formerly $316/$299/$283) are no longer published; plan prices appear only after the intake questionnaire.
'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.
Wisp
Monthly subscription supplement, NOT a prescription GLP-1 medication. 'subscription' in form keeps it out of the GLP-1 hero price. drug omitted intentionally.
Zepbound $99/mo (compounded sublingual semaglutide $225/mo)
What each price covers
Both prices cover the medication itself and shipping.
TrimRx's price also covers the clinician visit, which Wisp does not claim.
TrimRx is silent on lab work and coaching.
Wisp is silent on the clinician visit, lab work and coaching.
TrimRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Wisp
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, TrimRx scores 7.2 and Wisp 6.5 out of 10.
TrimRx is stronger on value (5.2 vs 3.5) and support (7.0 vs 4.5).
Effectiveness, user experience, trust & safety and accessibility are within half a point.
TrimRx
7.2/10
Wisp
6.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither TrimRx nor Wisp has an FDA warning letter on record with us.
Features & Coverage
| Feature | TrimRx | Wisp |
|---|---|---|
| Starting Price | $179/mo | ✓$99/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About TrimRx
Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.
Read our full TrimRx review →About Wisp
$225/month buys a compounded sublingual semaglutide drops formulation from Wisp. Its weight care vertical also stocks three brand names: Saxenda, Zepbound, and Wegovy. A board-certified provider completes the review inside 24-72 hours. LegitScript certification is in place.
Read our full Wisp review →Pros & Cons
TrimRx
What we like
- Semaglutide costs $179 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $259 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to TrimRx
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Wisp
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication and shipping
- We found no FDA warning letters issued to Wisp
Watch-outs
- Semaglutide costs $225 a month, 22% above the $184 median for compounded semaglutide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
TrimRx wins this one, 7.2 to 6.5, above all for compounded semaglutide at $179/month. Wisp undercuts it by $80 a month, so if the monthly bill is what decides it, Wisp is the pick. Wisp fits better if an oral route if you will not self-inject is your priority.
Choose TrimRx if…
You want compounded semaglutide at $179/month and an opening price near $179 a month.
Choose Wisp if…
You want an oral route if you will not self-inject and an opening price near $99 a month.
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Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →TrimRx vs Wisp: FAQ
Close alternatives to TrimRx and Wisp
- TrimRx vs GOAL.MD
- TrimRx vs Vaylen
- TrimRx vs DudeMeds
- TrimRx vs Healthicare
- Wisp vs GobyMeds
- Wisp vs HeliMeds
Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.