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TrimRx vs ShedRx

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
TrimRx logo

TrimRx

7.2
★★★3.6/5

Best for: compounded semaglutide at $179/month

Visit TrimRx
VS
ShedRx logo

ShedRx

6.4
★★★☆☆3.2/5

Best for: oral orforglipron alongside the injectables

Visit ShedRx

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, ShedRx opens cheaper — $149/mo against $179, and TrimRx finishes ahead, 7.2 to 6.4. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

TrimRx

Starting (flat across doses)Compounded
$179$135/mo
Save 25% right now
semaglutide

Homepage tier 'GLP-1 Starting at $179'; hero checkout mockup shows $299.00 list struck to $179.00/1st mo; email-capture popup offers '$120 OFF for your first order — GET YOUR FIRST MONTH AS LOW AS $135'. Multi-month bundle prices ($209/$191/$174 recorded 2026-07-10) are NO LONGER published — old public checkout 404s, plans now quiz-gated.

Starting (flat across doses)Compounded
$259/mo
tirzepatide

Homepage tier 'GLP-1 + GIP Starting at $259' (hero mockup: 'GLP-1 + GIP Medication Contains Tirzepatide') — DOWN from the $279 checkout limited offer we recorded 2026-07-10; bundle prices ($316/$299/$283) no longer published (quiz-gated).

StartingBrand-name
$1249/mo
tirzepatide (mounjaro)

'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.

StartingBrand-name
$1249/mo
tirzepatide (zepbound)

'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.

StartingBrand-name
$1579/mo
semaglutide (wegovy)

'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.

ShedRx

InjectableCompounded
$199$159/mo
Save 20% right now
semaglutide

$199 1-month / $179 6-month / $159 12-month plan; promo_price = 12-month commitment rate, not a temporary promo

DropsCompounded
$229/mo
semaglutide

Starting at $229/month; 'Medication and supplies included | Member support | Free shipping' (up from $199 in our record)

LozengesCompounded
$199/mo
semaglutide

Starting at $199/month, month-to-month; free shipping stated (replaces our obsolete 'Oral $349' row)

InjectableCompounded
$299$239/mo
Save 20% right now
tirzepatide

$299 1-month / $269 6-month / $239 12-month plan; promo_price = 12-month commitment rate

Daily pillCompounded · oral
$149/mo
orforglipron

NEW product. $149/mo medication (cash pay, paid to dispensing pharmacy) + $125/mo Shed membership and provider fee

Pen weekly / pill dailyCompounded
$149/mo
semaglutide

Page shows BOTH: FAQ 'starts at $149 (pill) and $199 (pen)... new patients using cash pay' + '$99 Shed membership', while hero states '$349-499 for the medication' + '$125/month Shed Membership'. Medication purchased directly via NovoCare; membership fee inconsistency ($99 vs $125) on same page

VialCompounded
$349/mo
tirzepatide

FAQ: 'starts at $349 per month for new patients using cash pay' + $99 membership per FAQ ($125/mo per hero); medication purchased directly via LillyDirect

DailyCompounded · oral
$169/mo
metformin + naltrexone + topiramate

Starting at $169/month; 'Includes 2 Health Coaching sessions per month'

What’s included

TrimRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

ShedRx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TrimRx

7.2/10

Overall

ShedRx

6.4/10

Value25%

5.4A
vs
B
6.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
3.0

Trust & Safety15%

6.5A
vs
B
4.0

Accessibility10%

5.0A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

Features & Coverage

FeatureTrimRxShedRx
Starting Price$179/mo$149/mo
Features8 features4 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About TrimRx

Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.

Read our full TrimRx review →

About ShedRx

ShedRx is a telehealth seller with three formats of compounded GLP-1 medication: drops, lozenges, and injections.

Read our full ShedRx review →

Pros & Cons

TrimRx

What we like

  • Semaglutide at $179 a month, within the normal band around this register's $189 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

ShedRx

What we like

  • Semaglutide at $149 a month, within the normal band around this register's $189 median for the same drug and form
  • The monthly figure covers medication, consult, coaching
  • No FDA warning letter matched this operator when we searched our enforcement register
  • Both oral and injectable options are on record, so the format is a choice rather than a condition

Watch-outs

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its orforglipron and semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: TrimRx

TrimRx takes it, 7.2 against 6.4, and it is especially strong on compounded semaglutide at $179/month. ShedRx is no weak second and may fit you better on oral orforglipron alongside the injectables.

Choose TrimRx if…

You want compounded semaglutide at $179/month and an opening price near $179 a month.

Choose ShedRx if…

You want oral orforglipron alongside the injectables and an opening price near $149 a month.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

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8.5

Strut Health

Semaglutide at $99/month, 48% under the register median

7.9

Oak

Semaglutide at $119/month, 37% under the register median

8.8

Found

Tirzepatide at $169/month, 37% under the register median

TrimRx vs ShedRx: FAQ

Glossary

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.