SkinnyRx vs TrimRx
SkinnyRx costs $29.75 less a month, and both sell semaglutide and tirzepatide.
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If you are choosing between SkinnyRx and TrimRx, the first difference is cost: SkinnyRx is $29.75 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. TrimRx leads our six-part score, 7.2 to 5.9. One of the two has an FDA warning letter on record, covered below.
SkinnyRx vs TrimRx price
SkinnyRx is the cheaper way in: $149.25 a month against $179 a month at TrimRx. That is $29.75 less each month (17% lower), or about $357 over a year of treatment.
Drug by drug: Semaglutide is cheaper at SkinnyRx ($149.25 a month vs $179 a month); tirzepatide is cheaper at SkinnyRx ($224.25 a month vs $259 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, SkinnyRx prices compounded injections and an oral option, while TrimRx prices compounded injections and brand-name pens.
If you want the FDA-approved brand rather than a compounded version, TrimRx is the only one of the two with a brand-name price.
Where each one treats patients
Neither SkinnyRx nor TrimRx publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
SkinnyRx
'As low as $149.25/mo*' — plan-length/promo dependent (matches the sitewide '25% lower prices' promo, $199 x 0.75); standard single-month rate not published pre-intake. Microdose available; free overnight shipping.
'As low as $199/mo*' on /products/semaglutide-oral; once-daily.
'As low as $249/mo*' on /products/semaglutide-tablets.
'As low as $224.25/mo*' and 'Starting at $224.25/mo with free overnight shipping'; microdose available; once-weekly.
'As low as $224.25/mo*' on /products/tirzepatide-tablets; once-daily.
'$1,400/mo*' — '*Price shown applies to Monthly plan paid upfront or with buy now, pay later programs.' 'No membership fees. Same price at every dose.'
'$1,400/mo*' on /products/wegovy-injectable. Wegovy PILL is listed 'Unavailable' ('available via SkinnyRx Membership', fee not published).
'$1,400/mo*' on /products/mounjaro.
'$1,400/mo*' on /products/zepbound. Foundayo (orforglipron) pill also listed but 'Unavailable' — price not published.
TrimRx
GLP-1 starts at $179. The homepage shows a $299.00 list price struck through to $179.00 for the first month, and an email sign-up offer promises '$120 OFF' your first order, for a first month as low as $135. Multi-month bundles (formerly $209/$191/$174) are no longer published; plan prices appear only after the intake questionnaire.
The GLP-1 + GIP plan, which contains tirzepatide, starts at $259, down from an earlier $279 limited offer. Multi-month bundles (formerly $316/$299/$283) are no longer published; plan prices appear only after the intake questionnaire.
'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
SkinnyRx is silent on lab work and coaching.
TrimRx is silent on lab work and coaching.
SkinnyRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
TrimRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, TrimRx scores 7.2 and SkinnyRx 5.9 out of 10.
SkinnyRx is stronger on value (6.5 vs 5.2).
TrimRx is stronger on user experience (8.0 vs 3.0) and trust & safety (6.5 vs 1.0).
Effectiveness, accessibility and support are within half a point.
SkinnyRx
5.9/10
TrimRx
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent SkinnyRx a warning letter dated February 20, 2026 (letter 717989), and it is still open.
TrimRx has no FDA warning letter on record with us.
Features & Coverage
| Feature | SkinnyRx | TrimRx |
|---|---|---|
| Starting Price | ✓$149.25/mo | $179/mo |
| Features | 3 features | ✓8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About SkinnyRx
SkinnyRx sells compounded semaglutide and tirzepatide as injectables, with a microdosing option, prescribed by licensed US clinicians. The consult and free overnight shipping are bundled into a single monthly cash price.
Read our full SkinnyRx review →About TrimRx
Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.
Read our full TrimRx review →Pros & Cons
SkinnyRx
What we like
- Semaglutide costs $149.25 a month, 19% below the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $224.25 a month, 10% below the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued SkinnyRx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
TrimRx
What we like
- Semaglutide costs $179 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $259 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to TrimRx
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
SkinnyRx is where we would start, above all for starting below a standard dose, with microdose tiers. It also costs $29.75 less each month than TrimRx. TrimRx fits better if compounded semaglutide at $179/month is your priority.
Choose SkinnyRx if…
You want starting below a standard dose, with microdose tiers and an opening price near $149.25 a month.
Choose TrimRx if…
You want compounded semaglutide at $179/month and an opening price near $179 a month.
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He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →SkinnyRx vs TrimRx: FAQ
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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.