Signos vs CoreAge Rx
An in-depth comparison of two leading GLP-1 Providers
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CoreAge Rx
Best for: semaglutide at $99/month, 48% under the register median
Visit CoreAge Rx →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, CoreAge Rx opens cheaper — $99/mo against $199, and CoreAge Rx finishes ahead, 9.1 to 6.8. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Signos
Signos+ GLP-1 bundle (tirzepatide OR semaglutide) from $199/mo; includes CGM system
CoreAge Rx
Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
What’s included
Signos
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
CoreAge Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Signos
6.8/10
CoreAge Rx
9.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Signos | CoreAge Rx |
|---|---|---|
| Starting Price | $199/mo | ✓$99/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Signos
Entry price is $199/mo, and that requires the 6-month plan; shipping is free and HSA/FSA cards work. What Signos+ adds to the prescription is hardware: an app plus a continuous glucose monitor cleared by the FDA, sitting alongside clinician-prescribed compounded semaglutide. Glucose readings arrive in real time with coaching attached, the stated aim being that a user grasps and then holds the loss. Its pitch is that this costs no more than the drug alone.
Read our full Signos review →About CoreAge Rx
Shipping is free, 2-day, and reaches all 50 states. CoreAge Rx sells LegitScript-verified compounded semaglutide plus tirzepatide, with licensed physicians behind it and 24/7 support. Its own claim: nobody in the compounded GLP-1 space prices more competitively.
Read our full CoreAge Rx review →Pros & Cons
Signos
What we like
- Semaglutide at $199 a month, within the normal band around this register's $189 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication and shipping
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
CoreAge Rx
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Tirzepatide at $149 a month, 44% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
CoreAge Rx takes it, 9.1 against 6.8, and it is especially strong on semaglutide at $99/month, 48% under the register median. Signos is no weak second and may fit you better on compounded semaglutide at $199/month.
Choose Signos if…
You want compounded semaglutide at $199/month and an opening price near $199 a month.
Choose CoreAge Rx if…
You want semaglutide at $99/month, 48% under the register median and an opening price near $99 a month.
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Telos Rx
Starting below a standard dose, with microdose tiers
From $49/mo
Get started →MyDrHank
An oral route if you will not self-inject
From $25/mo
Get started →SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →Signos vs CoreAge Rx: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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