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ShapeIn Rx vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
ShapeIn Rx logo

ShapeIn Rx

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $199/month

Visit ShapeIn Rx
VS
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $149, and He & She MD finishes ahead, 9.3 to 6.7. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

ShapeIn Rx

Compounded semaglutide with B12, monthlyCompounded
$199/mo
semaglutide

Advertised as Starting from $199/month. Homepage shows a struck $199 next to $149, but the $149 figure is attached to the liraglutide product.

Compounded liraglutide, daily injection, monthlyCompounded
$149/mo

Advertised as Starting from $149/month. Liraglutide is a daily rather than weekly injection. The drug field is omitted because liraglutide is not in the schema's drug enum.

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

What’s included

ShapeIn Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

ShapeIn Rx

6.7/10

Overall

He & She MD

9.3/10

Value25%

4.6A
vs
B
9.7

Effectiveness25%

8.5A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
8.5

Features & Coverage

FeatureShapeIn RxHe & She MD
Starting Price$149/mo$99/mo
Features5 features8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About ShapeIn Rx

WellHealth LLC runs this Phoenix-based telehealth service, selling compounded semaglutide with B12 and daily compounded liraglutide. Telemedicine is limited to the states where its providers are licensed.

Read our full ShapeIn Rx review →

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

Pros & Cons

ShapeIn Rx

What we like

  • Semaglutide at $199 a month, within the normal band around this register's $189 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 6.7, and it is especially strong on starting below a standard dose, with microdose tiers. ShapeIn Rx is no weak second and may fit you better on compounded semaglutide at $199/month.

Choose ShapeIn Rx if…

You want compounded semaglutide at $199/month and an opening price near $149 a month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

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9.4

Trimi Health

Knowing which pharmacy fills the vial — it names VialsRx

8.5

Strut Health

Semaglutide at $99/month, 48% under the register median

7.9

Oak

Semaglutide at $119/month, 37% under the register median

ShapeIn Rx vs He & She MD: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.