Sesame Care vs NextMeds
An in-depth comparison of two leading GLP-1 Providers
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NextMeds
Best for: semaglutide at $79/month, 59% under the register median
Visit NextMeds →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Sesame Care opens cheaper — $59/mo against $79, and NextMeds finishes ahead, 9.2 to 6.7. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Sesame Care
Month-to-Month $99/mo, 3-Month $39/mo, 6-Month $49/mo, Annual $59/mo; includes video visits, unlimited messaging, follow-ups, labs (savings $60/3mo, $180/6mo, $480/yr)
$199/mo first two months, new self-pay patients, lowest doses (0.25/0.5mg) only; FAQ terms state offer valid through 2026-06-30 but $199 still advertised on 2026-07-14
low doses
high doses; maintenance dose $50/mo cheaper than Wegovy injection
NEW published pricing: $199 first two months (same new-self-pay intro terms as Wegovy); 2mg is $499/mo
$399/mo for 5mg; $449/mo for 7.5mg, 10mg, 12.5mg, 15mg — unchanged vs stored
$399/mo 5mg, $499/mo 7.5mg, $699/mo 10-15mg (program page shows $398/$698 — Sesame's own pages disagree by $1)
NEW row on program page: 'Zepbound® Tirzepatide Starts at $1,086 per / mo' (retail-channel pen, distinct from LillyDirect KwikPen)
NEW published pricing: $199/mo (2.5mg), $299/mo (5.5mg, 9mg), $349/mo (14.5mg, 17.2mg); previously feature-only with no pricing row
'Price with insurance: as low as $25 per / mo.' — copay varies by plan/PA outcome
NextMeds
Compounded Semaglutide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $79 is the month-to-month rate read from the pricing section on 2026-08-14. The site headline reads 'from $49/mo': that is the 12-month prepaid term divided down, not a monthly price, and the ladder between them is 3-month $76, 6-month $73, 12-month $49. A summer promotion was running with a stated end of August 20, so $79 may itself be discounted.
Compounded Tirzepatide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $109 is the month-to-month rate read from the pricing section on 2026-08-14. The advertised 'GLP-1 + GIP: $95' is the 12-month prepaid term divided down; the ladder is 3-month $105, 6-month $100, 12-month $95. A summer promotion was running with a stated end of August 20, so $109 may itself be discounted.
What’s included
Sesame Care
Inclusions not disclosed.
NextMeds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Sesame Care
6.7/10
NextMeds
9.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Sesame Care | NextMeds |
|---|---|---|
| Starting Price | ✓$59/mo | $79/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Sesame Care
A subscription running $39-$99/month pays for the clinical care and nothing else; drugs are charged separately at cash rates, which includes Zepbound from $299 through LillyDirect and a Wegovy self-pay promotion at $199/month. Nothing in the weight-loss line is compounded, only branded. Rather than working off a stocked formulary the way most weight-loss platforms do, Sesame prices transparently and puts patients in touch with independent provider practices.
Read our full Sesame Care review →About NextMeds
Membership is a single flat monthly charge, and inside it sit free shipping, a registered dietitian holding a license, a care coach working 1:1, telehealth visits and the drug itself where one is prescribed. Insurance is not billed. A free assessment online goes to a licensed provider, who adds a phone or video consult in states that demand one, then prescribes if it fits. Compounding pharmacies within the Next Meds network, all licensed, ship. Auto-renewal does not exist, cancellation is open, and all 50 states can order compounded tirzepatide and semaglutide.
Read our full NextMeds review →Pros & Cons
Sesame Care
What we like
- Semaglutide at $149 a month, within the normal band around this register's $199 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Both oral and injectable options are on record, so the format is a choice rather than a condition
Watch-outs
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its orforglipron and semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
NextMeds
What we like
- Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
- Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
NextMeds takes it, 9.2 against 6.7, and it is especially strong on semaglutide at $79/month, 59% under the register median. Sesame Care is no weak second and may fit you better on oral orforglipron alongside the injectables.
Choose Sesame Care if…
You want oral orforglipron alongside the injectables and an opening price near $59 a month.
Choose NextMeds if…
You want semaglutide at $79/month, 59% under the register median and an opening price near $79 a month.
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MyDrHank
An oral route if you will not self-inject
From $25/mo
Get started →SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →YourEra
Semaglutide at $99/month, 63% under the register median
From $99/mo
Get started →Sesame Care vs NextMeds: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.